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csbm /m mice growth csbm /m liver figure level repair oxidative mouse csbm /m pups ageing metabolism animal damage expression wk-old dna damage oxidative metabolism d-old signi syndrome 0.000 table response littermate antioxidant defect somatotroph axis csbm /m animals analysis antioxidant defense gh /igf axis hormone cockayne control cockayne syndrome dna repair signi ficantly change biology 15- expression levels photoreceptor defense stress glycogen tissue postnatal photoreceptor loss somatotroph lifespan volume 0.001 issue ficantly sensitivity january growth hormone www.plosbiology.org phenotype serum protein van der pluijm glucose transcriptome csbm /m liver inactivation feature retina synthesis number family patient oxidative stress apoptotic cells genome photoreceptor cells staining polyp process
1 Most Recent Publications
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Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
(Article)
Pluijm, I. van der Garinis, G.A. Niedernhofer, L.J. Velasco, S. Friedberg, E.C. Tanaka, K. Steeg, H. van Hoeijmakers, J.H.J. Horst, G.T.J. van der Brandt, R.M.C. Gorgels, T.G.M.F. Wijnhoven, S.W.P. Diderich, K. Wit, J. de Mitchell, J.R. Oostrom, C.T.M. van Beems, R.B. |
2006-12-12
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