Goud, B.

bicd 1 –bicd rab 6 rab 6a dynein golgi microtubule vesicle nature gfp –bicd antibody structure protein transport 20 ° c bicd 2 transfected rab 6a vesicles 10 µ m microtubule minus-end-directed movement information dynein –dynactin hela cells movement interaction anti-rab 6 antibodies minus-end-directed cos 1 cells membrane velocity element control sirna gfp –rab scale bar c-terminal domain dynactin region cell biol gst –bicd antiserum overexpression nature cell biol microtubule minus-end-directed motion bicd 2-c cells bicd 1/rab tubules –dynactin number image trends cell biol copi-independent biology microtubule plus-end-directed motion untransfected hela cells /naturecellbiology antiserum 2296 function magnification publishing motion staining frame domain gtp -γs bicd 2-c www.nature.com group binding december figure communication arrow c-terminal rab 6aq protein extracts pathway anti-bicd tubules distribution plus-end-directed