View Author
scopus: 36963433000

Broekhof, J.L.M.

(Jose' Broekhof)


glycosylase dna glycosylase activity activity aag mice dna glycosylase lesion mouse dna glycosylases extract repair tissue liver oligonucleotide substrate teste protein dna lesions animal kidney agent aag liver extracts enzyme analysis oligonucleotide substrates cancer aag testes extracts excision hx dna glycosylase release alkyladenine dna glycosylase assay allele carcinogenesi samson genetic embryo abasic sites dna bases engelward 8 oxog aag embryos control method health dna glycosylase assays uracil aag exon ii protein extracts aag cdna 12- mer pathway nucleotide excision repair base excision repair aag animals time-dependent release aag cells science mouse embryo fibroblasts wild-type mutagenic abasic mouse liver c 57bl 6 material fragment primers alkyladenine generation study effect genotyping result sequence university me-lex mouse tissues product media oxoguanine repair systems




2 Most Recent Publications

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents. (Article)
Glassner, B.J. Weeda, G. Roth, R.B. Warren, H.B. Wu, M.M. Hoeijmakers, J.H.J. Samson, L.D. Allan, J.M. Broekhof, J.L.M. Carls, N.H.E. Donker, I. Engelward, B.P. Hampson, R.J. Hersmus, R. Hickman, M.J.
1999-05-20
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase. (Article)
Engelward, B.P. Weeda, G. Wyatt, M.D. Broekhof, J.L.M. Wit, J. de Donker, I. Allan, J.M. Gold, B. Hoeijmakers, J.H.J. Samson, L.D.
1997-01-01