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b cells expression protein figure b cell development mouse kinase development chain pre-b response number level tyrosine bone marrow fibulin analysis result spleen replication receptor pre-b cells antigen domain fraction activation stage mutation marrow wild-type e 41k transcription sequence region recombination repair tfiih differentiation fragment surface tyrosine kinase effect function phenotype activity x-linked antibody splenic transgene es cells hendrik background factor population signal pathway bruton damage chromosome 81à/à es cells b-cell table binding dna damage rearrangement control h 2ax foci chapter element btk-deficient model defect study promoter presence fibulin -4r mice serum locus patient transposition
10 Most Recent Publications
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Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
(Article)
Berge, D.T. Kurek, D.M. Blauwkamp, T. Koole, W. Maas, A. Eroglu, E. Siu, R.K. Nusse, R. |
2011-09-01
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Functional dissection of the Oct6 schwann cell enhancer reveals an essential role for dimeric sox10 binding
(Article)
Jagalur, N.B. Ghazvini, M. Mandemakers, W. Driegen, S. Maas, A. Jones, E.A. Grosveld, F.G. Jaegle, M. Svaren, J. Meijer, D.N. |
2011-06-08
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Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells
(Article)
Kersseboom, R. Kil, L. Flierman, R. Zee, M. van der Dingjan, G.M. Middendorp, S. Maas, A. Hendriks, R.W. |
2010-09-01
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Tagged mutagenesis by efficient minos-based germ line transposition
(Article)
Wit, T.P.M. de Dekker, S. Drabek, D.D. Maas, A. Breedveld, G.J. Knoch, T.A. Langeveld, A. Szumska, D. Craig, R. Bhattacharya, S. Grosveld, F.G. |
2010-01-01
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A mouse model for chronic lymphocytic leukemia based on expression of the SV40 large T antigen
(Article)
Brugge, P.J. ter Ta, T.B.V. Bruijn, M.J.W. de Keijzers, G. Maas, A. Gent, D.C. van Hendriks, R.W. |
2009-11-18
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Differentiation driven changes in the dynamic organization of basal transcription initiation
(Article)
Giglia-Mari, G. Theil, A.F. Fousteri, M.I. Hoeijmakers, J.H.J. Vermeulen, W. Mari, P.O. Mourgues, S. Nonnekens, J. Andrieux, L.O. Wit, J. de Miquel, C. Wijgers, N. Maas, A. |
2009-10-01
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Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
(Article)
Motegi, A. Liaw, H.J. Myung, K. Lee, K.Y. Roest, H.P. Maas, A. Wu, X. Moinova, H. Markowitz, S.D. Ding, H. Hoeijmakers, J.H.J. |
2008-08-26
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The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
(Article)
Hanada, K. Budzowska, M. Davies, S.L. Drunen, E. van Onizawa, H. Beverloo, H.B. Maas, A. Essers, J. Hickson, I.D. Kanaar, R. |
2007-11-01
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Surrogate-Light-Chain Silencing Is Not Critical for the Limitation of Pre-B Cell Expansion but Is for the Termination of Constitutive Signaling
(Article)
Loo, P.F. van Dingjan, G.M. Maas, A. Hendriks, R.W. |
2007-09-21
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Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice
(Article)
Hanada, K. Vermeij, M. Kanaar, R. Essers, J. Garinis, G.A. Waard, M. de Kunen, M. Myers, L. Maas, A. Duncker, D.J.G.M. Meijers, C. Dietz, H.C. |
2007-03-01
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