Terhaar Sive Droste, J.S.

protein colon biomarker cancer tumor author manuscript sample candidate fluid adenomas publication tissue onlinefirst research february american copyright november downloaded association figure colorectal control chi 3l mouse colorectal cancer patient 0.023 level expression control subjects proteomic candidate biomarkers proteome model table staining analysis diagnosis serum detection colon tumor tissues discovery tandem mass spectrometry mcm 4 count study subject identification screening candidate crc biomarkers fluid proteome crc screening mcm proteins colon tumor development crc precursor lesions development novel adenoma mouse model colon tumors colorectal adenomas sample complexity marker number colon tumor colon tissue crc patients factor mucosa tumor samples blood stage disease colon mucosa immunohistochemical fluid samples concentration spectrometry