Ratziu, V.

patient therapy combination resistance combination therapy hepatitis b hepatitis treatment month liver hepatology study hepatology 2012 vol entecavir disease lamivudine liver disease tenofovir rescue therapy cohort hbv dna lactic acidosis range response hbeag baseline serum level development adefovir cirrhosis adherence genotypic genotypic resistance mutation ef ficacy signi rescue university hospital eppendorf suppression germany virus hbv-dna multidrug journal 0.5 mg /dl liver cirrhosis analysis gastroenterology multidrug resistance 3 months hbsag side effects result department ficant signi ficant acidosi 520–526 1.0 mutant decompensation hamburg lactic 1.2 pre-treatment table probability safety treatment duration nucleo tenofovir disoproxil fumarate log rank test impairment resistance patterns creatinine hbv-dna undetectability drug resistance chb patients 3 adv