Wu, X.

shprh expression transgene pcna polyubiquitination polyubiquitination globin dna damage level 5 hs 3 yeast damage hek 293t cells pathway replication liver pcna ubiquitination bgt 14 uv irradiation pcna-ub number acids research hltf expression research fragment promoter mutation ubiquitination element analysis 1 nuclease analysis gene therapy irradiation mouse therapy copy numbers control panel copy transgenes 265 bp promoter polymerase protein yeast rad 5 depletion concatamer blot analysis ubc 13 repair motegi domain head dna dna replication mms 2 grosveld globin gene probe animal vector university treatment recombination liver rna chromosome genomic sw 480 cells sirna 5 hs 2 mutagenesi brdu incorporation dna-damaging agents k 63-linked polyubiquitination ts pathway dna replication forks junction rad 5 founder figure antibody multicopy activity nhgri