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expression erythroid differentiation protein factor control i /11 cells erythroid progenitors level progenitors figure erythroblast kinase phosphorylation blood foxo 3a globin /11 analysis target number activation receptor eif 4e promoter culture activity erythroid differentiation translation patient transcription presence polysome liver pi 3k erythropoiesi mouse proliferation binding regulation inhibitor tyrosine hemoglobin result erasmus mc gab 1 erasmu erythroid cells antibody btg 1 mutation study expansion pathway sequence panel recruitment wild-type sample hmg 20b c-kit epo-induced lcr-g growth absence gata 1 locus table domain volume medium polysome recruitment knockdown thalassemia transcript bag 1 terminal progenitor tumor effect
10 Most Recent Publications
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KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in -hemoglobinopathy patients
(Article)
Borg, J. Phylactides, M. Hou, J. Karkabouna, S. Lappa-Manakou, C. Özgür, Z. IJcken, W.F.J. van Lindern, M.M. von Grosveld, F.G. Georgitsi, M. Kleanthous, M. Philipsen, S. Bartsakoulia, M. Patrinos, G.P. Tafrali, C. Lederer, C.W. Felice, A.E. Papachatzopoulou, A. Kourakli, A. Stavrou, E.F. Christou, S. |
2012-10-01
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Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts
(Article)
Horos, R. IJspeert, H. Pospisilova, D. Sendtner, R. Andrieu-Soler, C. Taskesen, E. Nieradka, A. Cmejla, R. Touw, I.P. Lindern, M.M. von |
2012-01-05
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The DNA binding factor Hmg20b is a repressor of erythroid differentiation
(Article)
Esteghamat, F. Dijk, T.B. van Horos, R. Pourfarzad, F. Lindern, M.M. von Philipsen, S. Braun, H. Dekker, S. Linden, R. van der Hou, J. Fanis, P. Demmers, J.A. IJcken, W.F.J. van Özgü, Z. |
2011-09-01
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Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin
(Article)
Borg, J. Papadopoulos, P. Cassar, W. Galdies, R. IJcken, W.F.J. van Özgür, Z. Gillemans, N. Hou, J. Bugeja, M. Grosveld, F.G. Lindern, M.M. von Felice, A.E. Georgitsi, M. Patrinos, G.P. Philipsen, S. Gutiérrez, L. Grech, G. Fanis, P. Phylactides, M. Verkerk, J.H.M. Spek, P.J. van der Scerri, C.A. |
2010-08-01
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The miR-144/451 locus is required for erythroid homeostasis
(Article)
Rasmussen, K.D. Simmini, S. Abreu-Goodger, C. Bartonicek, N. Di Giacomo, M. Bilbao-Cortes, D. Horos, R. Lindern, M.M. von Enright, A.J. O'Carroll, D. |
2010-07-01
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Igbpl is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation
(Article)
Grech, G. Blázquez-Domingo, M. Kolbus, A. Bakker, W.J. Müllner, E.W. Beug, H. Lindern, M.M. von |
2008-10-01
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Tissue-specific splicing factor gene expression signatures
(Article)
Grosso, A.R. Gomes, A.Q. Barbosa-Morais, N.L. Caldeira, S. Thorne, N.P. Grech, G. Lindern, M.M. von Carmo-Fonseca, M. |
2008-09-08
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DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia
(Article)
Glasow, A. Barrett, A. Enver, T. Hildebrandt, G. Zelent, A. Petrie, K. Gupta, R. Boix-Chornet, M. Zhou, D.C. Grimwade, D. Gallagher, R. Lindern, M.M. von Waxman, S. |
2008-02-15
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Dynamic regulation of Gata factor levels is more important than their identity
(Article)
Ferreira, R. Wai, A. Shimizu, R. Gillemans, N. Rottier, R. Lindern, M.M. von Ohneda, K. Grosveld, F.G. Yamamoto, M. Philipsen, S. |
2007-06-15
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β-Globin active chromatin hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice
(Article)
Kooren, J.A. Palstra, R.J.T.S. Klous, P. Splinter, D. Lindern, M.M. von Grosveld, F.G. Laat, W.L. de |
2007-06-01
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