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tibolone treatment endometrial expression effect endometrium progesterone metabolite estrogen level wnt /β-catenin control tissue receptor cancer analysis progestagenic estrogenic group growth myometrium serum vagina regulation women profile /β-catenin result number dkk 1 prab -36 cells cell lines postmenopausal women study hormone patient process inhibition oh-tibolone tibolone treatment -36 activity proliferation apoptosi cycle sample table catenin ishikawa staining kloosterboer cluster ecc 1 cells 4- tibolone kloosterboer hj factor 21 days ishikawa cells postmenopausal transcription foxo 1 e 2 mpa gene expression netherland endocrinol ratio presence e 2 treatment estradiol response time points differentially network pathway prab -36 β- catenin erasmus univ rotterdam progesterone receptor myometrial downloaded
6 Most Recent Publications
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Progesterone inhibition of Wnt/β-catenin signaling in normal endometrium and endometrial cancer
(Article)
Wang, Y. Hanifi-Moghaddam, P. Burger, C.W. Fodde, R. Blok, L.J. Hanekamp, E.E. Kloosterboer, H.J. Franken, P.F. Veldscholte, J. Doorn, H.C. van Ewing, P.C. Kim, J.J. Grootegoed, J.A. |
2009-09-15
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Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina
(Article)
Hanifi-Moghaddam, P. Boers-Sijmons, B. Klaassens, A.H.A. Wijk, F.H. van IJcken, W.F.J. van Spek, P.J. van der Verheul, H.A.M. Kloosterboer, H.J. Burger, C.W. Blok, L.J. |
2008-02-01
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Molecular analysis of human endometrium: Short-term tibolone signaling differs significantly from estrogen and estrogen + progestagen signaling
(Article)
Hanifi-Moghaddam, P. Boers-Sijmons, B. Blok, L.J. Klaassens, A.H.A. Wijk, F.H. van Bakker, M.A. den Ott, M.C. Shipley, G.L. Verheul, H.A.M. Kloosterboer, H.J. Burger, C.W. |
2007-05-01
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Levels of tibolone and estradiol and their nonsulfated and sulfated metabolites in serum, myometrium, and vagina of postmenopausal women following treatment for 21 days with tibolone, estradiol, or estradiol plus medroxyprogestrone acetate
(Article)
Verheul, H.A.M. Blok, L.J. Burger, C.W. Hanifi-Moghaddam, P. Kloosterboer, H.J. |
2007-02-01
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Molecular portrait of the progestagenic and estrogenic actions of tibolone: behavior of cellular networks in response to tibolone.
(Article)
Hanifi-Moghaddam, P. Gielen, S.C.J.P. Blok, L.J. Kloosterboer, H.J. Gooyer, M.E. de Sijbers, A.M. Gool, A.J. van Smid, M. Moorhouse, M.J. Wijk, F.H. van Burger, C.W. |
2005-02-01
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Progestogenic effects of tibolone on human endometrial cancer cells
(Article)
Blok, L.J. Ruiter, P.E. de Kuhne, E.C. Hanekamp, E.E. Grootegoed, J.A. Smid-Koopman, E. Gielen, S.C.J.P. Gooyer, M.E. de Kloosterboer, H.J. Burger, C.W. |
2003-01-01
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