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receptor effect som 230 expression release somatostatin adenomas level treatment corticotroph subtype sst 5 patient corticotroph adenomas sst 2 study acth release sst 5 receptors adenoma endocrinology binding analog secretion culture cushing control other -20 cells glucocorticoid journal endocrinol crh-induced acth release hormone metab value van koetsveld pm lambert medium disease -14 ifn-b regulation signi growth tumor inhibition -20 gh release basal acth release tissue ic 50 values sst 5 mrna acth secretion mouse analysis concentration syndrome fland lj incubation huvec octreotide ifn-a herder ww expression levels prl secretion signi ficantly cortisol number grade hmvec-l lamberts sw sst 2 expression interferon ss -14 20 cells basal adenoma cells tt cells presence prolactinoma
6 Most Recent Publications
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Effects of interferons α/β on the proliferation of human micro- and macrovascular endothelial cells
(Article)
Erdmann, J. Vitale, G. Koetsveld, P.M. van Croze, E. Sprij-Mooij, D. Hofland, L.J. Eijck, C.H.J. van |
2011-05-01
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Differential regulation of human dopamine D2 and somatostatin receptor subtype expression by glucocorticoids in vitro
(Article)
Bruin, C. de Feelders, R.A. Waaijers, A.M. Koetsveld, P.M. van Sprij-Mooij, D. Lamberts, S.W.J. Hofland, L.J. |
2009-05-18
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Coexpression of dopamine and somatostatin receptor subtypes in corticotroph adenomas
(Article)
Bruin, C. de Pereira, A.M. Hofland, L.J. Feelders, R.A. Romijn, J.A. Roelfsema, F. Sprij-Mooij, D. Aken, M.O. van Lelij, A.J.D. van Herder, W.W. de Lamberts, S.W.J. |
2009-04-01
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Distinct functional properties of native somatostatin receptor subtype 5 compared with subtype 2 in the regulation of ACTH release by corticotroph tumor cells.
(Article)
Hoek, J. van der Waaijers, M. Culler, M.D. Lamberts, S.W.J. Hofland, L.J. Koetsveld, P.M. van Sprij-Mooij, D. Feelders, R.A. Schmid, H.A. Schoeffter, P. Hoyer, D. Cervia, D. Taylor, J.E. |
2005-08-01
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The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5.
(Article)
Hofland, L.J. Hoek, J. van der Beckers, A. Lamberts, S.W.J. Feelders, R.A. Aken, M.O. van Koetsveld, P.M. van Waaijers, M. Sprij-Mooij, D. Bruns, C. Weckbecker, G. Herder, W.W. de |
2005-04-01
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The novel somatostatin analog SOM230 is a potent inhibitor of hormone release by growth hormone- and prolactin-secreting pituitary adenomas in vitro
(Article)
Hofland, L.J. Lely, A.J. van der Weckbecker, G. Feelders, R.A. Lamberts, S.W.J. Beckers, A. Hoek, J. van der Koetsveld, P.M. van Herder, W.W. de Waaijers, M. Sprij-Mooij, D. Bruns, C. |
2004-01-01
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