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globin locus expression region figure globin genes β- globin gene protein mouse effect chromatin globin loci b globin locus number transcription analysis pufferfish promoter chromosome hemoglobin β- globin locus control signal fragment deletion b globin gene cosmid result γ- globin genes position dnase sequence probe globin gene level grosveld blood concentration background liver wijgerde factor element adult genome chromatin structure suv 39h drosophila ∆-2.5 kb yac erythroid 16orf globin locus homologue dnase i sensitivity transgene eklf +/± background activation structure d.p.c centromeric table i table increase erythroid cells milot ¯uence cytoglobin hypersensitive line 3 decrease rubripe hybridization development 5¢- ¯uence pev c 16orf genes pc-g proteins chromatin ® bres dnasei b globin promoter
3 Most Recent Publications
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Functional and comparative analysis of globin loci in pufferfish and humans
(Article)
Gillemans, N. Tan-Un, K. Langeveld, A. Higgs, D. Philipsen, J.N.J. Grosveld, F.G. McMorrow, T. Tewari, R. Wai, A.W. Burgtorf, C. Drabek, D.D. Ventress, N. |
2003-01-01
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Activation of the beta β globin locus by transcription factors and chromatin modifiers.
(Article)
McMorrow, T. Wijngaard, A. van den Trimborn, T. Lohuizen, M. van Jenuwein, T. Djabali, M. Philipsen, J.N.J. Fraser, P. Grosveld, F.G. Milot, E. |
2000-01-01
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Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression.
(Article)
Calzolari, R. McMorrow, T. Yannoutsos, N. Langeveld, A. Grosveld, F.G. |
1999-02-15
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