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plaque shear stress shear stress lesion atherosclerosi macrophage atherosclerotic expression study artery 1 e -07 chemokine region fractalkine carotid figure activity atherosclerotic plaques muscle cells effect blood arginase receptor vessel carotid artery segment atherosclerotic lesions oscillatory shear stress 9 weeks wall shear stress circulation animal contrast collagen lipid -07 protein phenotype model cast placement inhibition result development level muscle accumulation response antibody chapter activation difference control cxcl 10 oscillatory disease mechanism analysis group composition system section monocyte gelatinolytic activity factor gelatinolytic oxldl tissue rabbit value van haperen r t-cell rupture formation plaque rupture agent wss values subset distribution arterioscler
10 Most Recent Publications
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Arginase inhibition prevents the low shear stress-induced development of vulnerable atherosclerotic plaques in ApoE-/- mice
(Article)
Olivon, V.C. Fraga-Silva, R.A. Silva, R.F. da Segers, D. Demougeot, C. Oliveira, A.M. de Savergnini, S.S. Berthelot, A. Crom, R. de Krams, R. Stergiopulos, N. |
2013-04-01
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Atherosclerotic Plaque Vulnerability in Experimental Models of Atherosclerosis
(Doctoral Thesis)
Segers, D. |
2011-11-23
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Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque
(Article)
Bochove, G.S. van Paulis, L.E. Segers, D. Mulder, W.J. Krams, R. Nicolay, K. Strijkers, G.J. |
2011-01-01
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Ex vivo and in vivo regulation of arginase in response to wall shear stress
(Article)
Silva, R.F. da Olivon, V.C. Segers, D. Crom, M.P.G. de Stergiopuloss, N. Krams, R. |
2010-10-11
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Atherosclerosis: Cell biology and lipoproteins - Shear stress and inflammation in plaque formation: New evidence
(Article)
Segers, D. Weinberg, P. Krams, R. |
2008-12-01
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Large variations in absolute wall shear stress levels within one species and between species
(Article)
Cheng, C. Helderman, F. Haperen, R. van Wentzel, J.J. Gijsen, F.J.H. Steen, A.F.W. van der Crom, R. de Krams, R. Tempel, D. Segers, D. Hierck, B.P. Poelmann, R.E. Tol, A. van Duncker, D.J.G.M. Robbers-Visser, D. Ursem, N.T.C. |
2007-12-01
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Effect of shear stress on vascular inflammation and plaque development
(Article)
Helderman, F. Segers, D. Crom, R. de Hierck, B.P. Poelmann, R.E. Evans, P.C. Krams, R. |
2007-10-01
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Shear stress-induced changes in atherosclerotic plaque composition are modulated by chemokines
(Article)
Cheng, C. Tempel, D. Crom, R. de Krams, R. Haperen, R. van Boer, H.C.J. de Segers, D. Huisman, M. Zonneveld, A.J. van Leenen, P.J.M. Steen, A.F.W. van der Serruys, P.W.J.C. |
2007-03-01
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Gelatinolytic activity in atherosclerotic plaques is highly localized and is associated with both macrophages and smooth muscle cells in vivo
(Article)
Segers, D. Helderman, F. Krams, R. Cheng, C. Damme, L.C.A. van Tempel, D. Boersma, H. Serruys, P.W.J.C. Crom, R. de Steen, A.F.W. van der Holvoet, P. |
2007-02-01
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Inflammation and atherosclerosis: mechanisms underlying vulnerable plaque.
(Article)
Krams, R. Segers, D. Feyter, P.J. de Gourabi, B.M. Maat, W. Cheng, K.L. Pelt, C. van Damme, L.C.A. van Steen, T. van der Korte, C.L. de Serruys, P.W.J.C. |
2003-01-01
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