Saris, J.J.

prorenin renin receptor angiotensin level binding medium ang i incubation angiotensinogen heart activation plasma ang ii myocyte m 6p receptors fluid generation prorenin binding effect study inhibitor presence schalekamp madh 4 hours protein enzyme mannose cardiomyocyte danser tissue angiotensin ii saxena pr 37° c fibroblast phosphate intracellular result schalekamp synthesis hypertension concentration man -6-p receptors danser ahj derkx fhm growth uptake internalization protease circulation figure factor absence blood experiment saxena derkx serum system angiotensin generation conversion huvec evidence release infusion lamers jmj culture 37° activity production angiotensin i control forearm prorcnin rat cardiomyocytes intracellular angiotensin generation condition renin-angiotensin system dna synthesis chapter