Abbou, M.

patient mutation tumor family history germ-line family sdhd mutations sdhd gene history germ-line sdhd mutations paraganglioma analysis germ-line sdhd mutation netherland carotid body sscp analysis pgl patients 200 control alleles missense onset sdhd mutation 13 patients missense mutations carotid pathology 92y l 95p study josephine nefkens institute department founder erasmus mc subunit genet 57 patients gene mutations cancer diagnosis region erasmu pattern result sequence alteration sequencing carotid body tumors information tissue sample evidence sdhd gene mutations pgl tumor control characteristic sdhd germ-line mutations exon 3 mutations t test dehydrogenase germ-line dna germ-line mutations succinate cornelisse l 139p detection l 139p mutation jansen devilee polymorphism follow-up hospital management codon difference specimen allele nerve van marck glomus tumours protein tumor dna resection