Boxtel, D. van

cloacae mutant fragili strain abscess antibiotic resistance cloacae 22491 culture effect activity agents chemother concentration infection parent strain cloacae 22491 mutants czx-resistant chemother enterobacter study plate treatment antimicrob group log 10 cfu lactamase cephalosporin agent czx-resistant e 16 times fragilis atcc 23745 susceptibility ec 50 profile parent bacteria frequency fragilis e cloacae 032349 fragilis mutants inocula model combination count table ed 50 number czx-resistant mutants antibiotic concentrations enzyme selection therapy 108 cfu /ml ed 50s control agar plates lactam bacteroide abscess development development difference emergence antibiotic-free agar cloacae mutants netherland 30 min enterobacter strains inoculum fragilis strain fragilis-e pt doses enterobacter cloacae abscess combinations ratio bacteroides fragilis antimicrobial 2001. 105 cfu /ml stearne cloacae 032349 combination