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Greaves, D.R.

( D.R. Greaves)


globin expression figure mouse region probe level fragment p-globin population 8- globin gene dnaase locus grosveld minilocu control sequence dnaase i digestion number hypersensitive clone p-globin gene 3-globin copy number hypersensitive sites analysis result 6- globin gene deletion kollia tk-neo b-globin thy-l liver effect promoter globin genes enhancer transfected nuclei erythroid bamhl f 3-globin gene tissue digestion mel cells b-globin gene tk-neo gene hybridized cosmid factor sample expression levels transcription presence position gel electrophoresis erythroid cells nuclease protection analysis k 562 cells ecorl experiment antoniou thy-l gene 0.3 yolk sac dna 0.3 x ssc dnaase l-hypersensitive sites k 562 populations l cell populations dnaasel control regions induction hindlll 6- globin minilocus globin gene brain 0.2 l-hypersensitive s-globin gene




6 Most Recent Publications

Importance of globin gene order for correct developmental expression. (Article)
Hanscombe, O. Whyatt, D. Fraser, P. Yannoutsos, N. Greaves, D.R. Dillon, N. Grosveld, F.G.
1991-01-01
A transgenic mouse model of sickle cell disorder. (Article)
Greaves, D.R. Fraser, P. Vidal, M.A. Hedges, M.J. Ropers, D. Luzzatto, L. Grosveld, F.G.
1990-01-01
The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner (Article)
Blom van Assendelft, M. Hanscombe, O. Grosveld, F.G. Greaves, D.R.
1989-01-01
A dominant control region from the human β-globin locus conferring integration site-independent gene expression. (Article)
Talbot, D. Collis, P. Antoniou, M. Vidal, M. Grosveld, F.G. Greaves, D.R.
1989-01-01
High-level, erythroid specific, expression of the human α-globin gene in transgenic mice and the production of human haemoglobin in murine erythrocytes. (Article)
Hanscombe, O. Vidal, M. Kaeda, J. Luzzatto, L. Greaves, D.R. Grosveld, F.G.
1989-01-01
Position-independent high level expression of the human β-globin gene in transgenic mice. (Article)
Grosveld, F.G. Blom van Assendelft, G. Greaves, D.R. Kollias, G.
1987-01-01