View Author
Coughtrie, M.W.
( M.W. Coughtrie)
sulfation liver sulfotransferase sult 1a sult 1e iodothyronine e 2 sulfation sulfate library erasmus mc substrate cytosol sulfatase thyroid activity inhibition hormone kidney rsult value concentration enzyme visser protein iodothyronines 0.1 phah-oh effect tissue result metab endocrinol thyroid hormone rat liver 30- min incubation triiodothyronine reaction conditions microsome erasmu study reaction downloaded incubation placenta iodothyronine sulfates liver cytosol condition visser tj falany km values experiment v 79 cells rat liver microsomes kidney cytosol metabolism brain library endocrinology expression rat liver cytosol kaptein e rsult 1b phenol arylsulfatase liver microsomes table thyroid hormone metabolism triiodothyronine sulfate estrogen november triplicate determinations kaptein km value ic 50 values hydroxylated falany cn characterization compound cytosolic inhibitor brain cytosol
6 Most Recent Publications
|
Characterization of rat iodothyronine sulfotransferases.
(Article)
Kester, M.H.A. Kaptein, E. Roest, T.J. Dijk, C.H. van Tibboel, D. Meinl, W. Glatt, H. Coughtrie, M.W. Visser, T.J. |
2003-01-01
|
|
Characterization of iodothyronine sulfatase activities in human and rat liver and placenta
(Article)
Kester, M.H.A. Kaptein, E. Dijk, C.H. van Roest, T.J. Tibboel, D. Coughtrie, M.W. Visser, T.J. |
2002-01-01
|
|
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters
(Article)
Kester, M.H.A. Visser, T.J. Brouwer, A. Bulduk, S. Toor, H. van Tibboel, D. Meinl, W. Glatt, H. Falany, C.N. Coughtrie, M.W. Schuur, A.G. |
2002-01-01
|
|
Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs
(Article)
Kester, M.H.A. Bergman, A. Falany, C.N. Coughtrie, M.W. Kuiper, G.G.J.M. Safe, S.H. Visser, T.J. Brouwer, A. Schuur, A.G. Bulduk, S. Tibboel, D. Meinl, W. Glatt, H. |
2000-01-01
|
|
Characterization of human iodothyronine sulfotransferases
(Article)
Kester, M.H.A. Kaptein, E. Roest, T.J. Dijk, C.H. van Tibboel, D. Meinl, W. Glatt, H. Coughtrie, M.W. Visser, T.J. |
1999-01-01
|
|
Sulfation of thyroid hormone by estrogen sulfotransferase
(Article)
Kester, M.H.A. Visser, T.J. Coughtrie, M.W. Dijk, C.H. van Tibboel, D. Hood, A.M. Rose, N.J. Meinl, W. Pabel, U. Glatt, H. Falany, C.N. |
1999-01-01
|
