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transcription locus globin chromatin enhancer promoter factor interaction region globin locus expression element protein erythroid binding b-globin fragment globin genes control chromosome b-globin locus transcription factors ef-tu study model transcriptional figure beta-globin grosveld histone erythroid cells looping sequence mouse differentiation frequency analysis level formation function liver domain gene expression rna polymerase ii structure activation regulation polymerase hypersensitive binding sites ldb 1 activity cross-linking frequencies development mechanism result cross-linking genomic hypersensitive sites experiment dna elements chromatin hub contact nature palstra globin gene restriction genet chapter locus control region distance groudine cis-regulatory elements nucleus globin lcr oca 2 promoter genome proximity cluster organisation
10 Most Recent Publications
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Transcription factor binding at enhancers: Shaping a genomic regulatory landscape in flux
(Article)
Palstra, R.J.T.S. Grosveld, F.G. |
2012-12-01
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HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter
(Article)
Visser, M. Kayser, M. Palstra, R.J.T.S. |
2012-03-01
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The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation
(Article)
Soler, E. Andrieu-Soler, C. Hou, J. Steinhoff, C. Rijkers, E.J. Lenhard, B. Grosveld, F.G. Boer, E. de Bryne, J.C. Thongjuea, S. Stadhouders, R. Palstra, R.J.T.S. Stevens, M. Kockx, C. IJcken, W.F.J. van |
2010-02-01
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Close encounters of the 3C kind: Long-range chromatin interactions and transcriptional regulation
(Article)
Palstra, R.J.T.S. |
2009-10-02
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Maintenane of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription
(Article)
Palstra, R.J.T.S. Simonis, M. Klous, P. Brasset, E. Eijkelkamp, B. Laat, W.L. de |
2008-02-20
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Three-Dimensional Organization of Gene Expression in Erythroid Cells
(Article)
Laat, W.L. de Klous, P. Kooren, J.A. Noordermeer, D. Palstra, R.J.T.S. Simonis, M. Splinter, D. Grosveld, F.G. |
2008-02-18
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Chapter 4 β-Globin Regulation and Long-Range Interactions
(Article)
Palstra, R.J.T.S. Laat, W.L. de Grosveld, F.G. |
2008-02-18
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β-Globin active chromatin hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice
(Article)
Kooren, J.A. Palstra, R.J.T.S. Klous, P. Splinter, D. Lindern, M.M. von Grosveld, F.G. Laat, W.L. de |
2007-06-01
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Elongation factor Tu3 (EF-Tu3) from the kirromycin producer Streptomyces ramocissimus is resistant to three classes of EF-Tu-specific inhibitors
(Article)
Olsthoorn-Tieleman, L.N. Palstra, R.J.T.S. Wezel, G.P. van Bibb, M.J. Pleij, C.W.A. |
2007-05-01
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Spatial organisation of the ß-globin locus
(Doctoral Thesis)
Palstra, R.J.T.S. |
2005-01-05
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