Sibbles, B.

patient disease glucosidase treatment muscle pompe disease 4 patients pompe enzyme rhaglu month study rabbit glycogen therapy rotterdam glucosidase activity 40 mg /kg enzyme replacement therapy rabbit milk production 20 mg /kg development activity storage infant netherland alpha-glucosidase mutation muscle function 4 years protein erasmus mc-sophia function 1 year 12 weeks reuser aj baseline lysosomal fabry disease patient 3 van der ploeg infusion erasmu motor 110- kda precursor tissue efficacy inclusion effect reuser patients 1 erasmus mc department quadriceps muscle patient 1 hypertrophy acid alpha-glucosidase 3 months number pediatrics replacement ventilator 37 months phase lysosomal acid alpha-glucosidase glycogenosis type ii animal j hum genet pompe disease fig j biol chem change genet method hum mol genet 2 years fabry glucosidase gene muscle strength patient 4