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tfiih protein transcription repair activity subunit factor antibody mutation fraction helicase damage figure polymerase function hoeijmaker dna repair kinase hmms 19 level rna polymerase ii analysis reaction lesion defect yeast dna damage syndrome tfiih subunits sug 1 allele assay interaction vermeulen xpdttd dtxpb expression nucleotide domain basal cancer ttd mice experiment mo 15 patient rna pol ii addition result nucleotide excision repair uv irradiation cockayne dtxpb protein gfp-csb / xpc effect presence control synthesis purification phosphorylation extract complex buffer sequence acids research promoter erasmus mc ttd-a vector genome k 48r compound atpase tc-ner tfiihmut nature fibroblast downloaded weeda xeroderma pigmentosum
10 Most Recent Publications
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A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair
(Article)
Anindya, R. Mari, P.O. Kristensen, U. Kool, H. Giglia-Mari, G. Mullenders, L.H.F. Fousteri, M.I. Vermeulen, W. Egly, J-M. Svejstrup, J.Q. |
2010-06-11
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Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.
(Article)
Andressoo, J.O. Jans, J. Boer, J. de Hoeijmakers, J.H.J. Horst, G.T.J. van der Mitchell, J.R. Egly, J-M. Wit, J. de Coin, F. Hoogstraten, D. Ven, H.W.M. van de Toussaint, W. Huijmans, J. Thio, H.B. Leeuwen, W.J. van |
2006-10-30
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Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.
(Article)
Compe, E. Drane, P. Laurent, C. Diderich, K. Braun, C. Hoeijmakers, J.H.J. Egly, J-M. |
2005-07-01
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A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A
(Article)
Giglia-Mari, G. Coin, F. Botta, E. Stefanini, M. Aebersold, R. Hoeijmakers, J.H.J. Vermeulen, W. Egly, J-M. Ranish, J.A. Hoogstraten, D. Theil, A. Wijgers, N. Jaspers, N.G.J. Raams, A. Argentini, M. Spek, P.J. van der |
2004-07-01
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DNA damage stabilizes interaction of CSB with the transcription elongation machinery
(Article)
Boom, V. van den Citterio, E. Hoogstraten, D. Zotter, A.M. Cappellen, W.A. van Houtsmuller, A.B. Vermeulen, W. Hoeijmakers, J.H.J. Egly, J-M. |
2004-01-01
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A human homolog of the yeast nucleotide excision repair gene MMS19 interacts with transcription repair factor TFIIH through the XPB and XPD helicases.
(Article)
Seroz, T. Winkler, G.S. Hoeijmakers, J.H.J. Auriol, J. Verhage, R.A. Vermeulen, W. Smit, B. Brouwer, J. Eker, A.P.M. Weeda, G. Egly, J-M. |
2000-01-01
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TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair
(Article)
Winkler, G.S. Fiedler, U. Vermeulen, W. Coin, F. Wood, R.D. Timmers, H.T. Weeda, G. Hoeijmakers, J.H.J. Araújo, S.J. Egly, J-M. |
2000-01-01
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Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases
(Article)
Seroz, T. Winkler, G.S. Egly, J-M. Auriol, J. Verhage, R.A. Vermeulen, W. Smit, B. Brouwer, J. Weeda, G. Hoeijmakers, J.H.J. Eker, A.P.M. |
2000-01-01
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Affinity purification of the human DNA repair/transcription factor TFIIH using (epitope) tagged XPB.
(Article)
Winkler, G.S. Vermeulen, W. Coin, F. Hoeijmakers, J.H.J. Weeda, G. Egly, J-M. |
1998-01-09
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Affinity purification of human DNA repair/transcription factor TFIIH using epitope-tagged xeroderma pigmentosum B protein
(Article)
Winkler, G.S. Vermeulen, W. Coin, F. Weeda, G. Hoeijmakers, J.H.J. Egly, J-M. |
1998-01-01
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