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repair protein mouse figure damage wild-type allele transcription analysis mutation animal defect −/− sensitivity cancer tfiih level syndrome mhr 6a es cells result lesion sequence yeast patient expression recombination hoeijmaker function clone oxidative survival ttd mice group fragment dna damage experiment pathway cockayne dna repair xeroderma number phenotype embryo activity response effect cerevisiae van der horst pigmentosum xpdttd genomic xpbxpc strand light exposure excision probe tissue genome blot analysis photolyase csbm /m mice knockout synthesis table liver histone feature mutant cell lines development xeroderma pigmentosum agent growth region model fibroblast control homolog
10 Most Recent Publications
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Decentralised management of solid waste in Mumbai slums: Informal privatisation through patronage
(Article)
Wit, J. de |
2010-11-02
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Differentiation driven changes in the dynamic organization of basal transcription initiation
(Article)
Giglia-Mari, G. Theil, A.F. Fousteri, M.I. Hoeijmakers, J.H.J. Vermeulen, W. Mari, P.O. Mourgues, S. Nonnekens, J. Andrieux, L.O. Wit, J. de Miquel, C. Wijgers, N. Maas, A. |
2009-10-01
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An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair
(Article)
Andressoo, J.O. Weeda, G. Wit, J. de Mitchell, J.R. Beems, R.B. Steeg, H. van Horst, G.T.J. van der Hoeijmakers, J.H.J. |
2009-03-01
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Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts
(Article)
Waard, H. de Sonneveld, E. Wit, J. de Esveldt-van Lange, R. Hoeijmakers, J.H.J. Vrieling, H. Horst, G.T.J. van der |
2008-10-01
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Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
(Article)
Pluijm, I. van der Garinis, G.A. Niedernhofer, L.J. Velasco, S. Friedberg, E.C. Tanaka, K. Steeg, H. van Hoeijmakers, J.H.J. Horst, G.T.J. van der Brandt, R.M.C. Gorgels, T.G.M.F. Wijnhoven, S.W.P. Diderich, K. Wit, J. de Mitchell, J.R. Oostrom, C.T.M. van Beems, R.B. |
2006-12-12
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Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles.
(Article)
Andressoo, J.O. Jans, J. Boer, J. de Hoeijmakers, J.H.J. Horst, G.T.J. van der Mitchell, J.R. Egly, J-M. Wit, J. de Coin, F. Hoogstraten, D. Ven, H.W.M. van de Toussaint, W. Huijmans, J. Thio, H.B. Leeuwen, W.J. van |
2006-10-30
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Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage.
(Article)
Waard, H. de Wit, J. de Andressoo, J.O. Oostrom, C.T.M. van Riis, B. Weimann, A. Poulsen, H.E. Steeg, H. van Hoeijmakers, J.H.J. Horst, G.T.J. van der |
2004-09-01
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The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.
(Article)
Roest, H.P. Baarends, W.M. Wit, J. de Klaveren, J.W. van Wassenaar, E. Hoogerbrugge, J.W. Cappellen, W.A. van Hoeijmakers, J.H.J. Grootegoed, J.A. |
2004-06-01
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The ubiquitin-conjugating DNA repair enzyme is a maternal factor essential for early embryonic development in mice
(Article)
Roest, H.P. Baarends, W.M. Wit, J. de Klaveren, J.W. van Wassenaar, E. Hoogerbrugge, J.W. Cappellen, W.A. van Hoeijmakers, J.H.J. Grootegoed, J.A. |
2004-01-01
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The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA insterstrand cross-link-induced double-strand breaks
(Article)
Niedernhofer, L.J. Odijk, H. Kanaar, R. Budzowska, M. Drunen, E. van Maas, A. Theil, A.F. Wit, J. de Beverloo, H.B. Hoeijmakers, J.H.J. Jaspers, N.G.J. |
2004-01-01
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