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protein repair ubiquitin yeast sequence rad 6 hhr 6a enzyme probe region mouse expression prakash hhr 6b histone koken figure degradation analysis homolog clone fragment function dna repair spermatid residue genomic chromosome nucleotide testi spermatogenesi hoeijmaker excision level pathway tissue hhr 6 proteins transcript chromatin ercc -7 hybridization domain rad 6 gene sporulation defect position plasmid homology result mutation group process ofthe drosophila transcription strain nature method mutagenesi blot analysis nat !. acad mutant system rad 6 protein structure cerevisiae rad 6 homologs yeast rad 6 bootsma signal encode ubiquitination reynold rhp 6+ gene response whieh ••• isolation number s.pombe
10 Most Recent Publications
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Isolation of human DNA repair genes based on nucleotide sequence conservation
(Doctoral Thesis)
Koken, M.H.M. |
1996-10-23
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Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.
(Article)
Klaveren, J. van Wit, J. de Hoeijmakers, J.H.J. Roest, H.P. Gurp, C.G. van Koken, M.H.M. Vermey, M. Roijen, J.H. van Vreeburg, J.T.M. Baarends, W.M. Bootsma, D. Grootegoed, J.A. |
1996-09-06
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Expression of the ubiquitin-conjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification.
(Article)
Koken, M.H.M. Hoogerbrugge, J.W. Jaspers-Dekker, I. Wit, J. de Willemsen, R. Roest, H.P. Grootegoed, J.A. Hoeijmakers, J.H.J. |
1996-01-10
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Postmeiotic transcription of X and Y chromosomal genes during spermatogenesis in the mouse.
(Article)
Hendriksen, P.J.M. Hoogerbrugge, J.W. Koken, M.H.M. Hoeijmakers, J.H.J. Oostra, B.A. Lende, T. van der Grootegoed, J.A. Themmen, A.P.N. |
1995-08-01
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Augmentation of protein production by a combination of the T7 RNA polymerase system and ubiquitin fusion: Overproduction of the human DNA repair protein, ERCC1, as a ubiquitin fusion protein in Escherichia coli.
(Article)
Koken, M.H.M. Odijk, J.H. Duin, M. van Fornerod, M.W.J. Bootsma, D. Hoeijmakers, J.H.J. |
1993-01-01
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Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosome Xq24-25 and 5q23-31.
(Article)
Koken, M.H.M. Smit, E.M.E. Jaspers-Dekker, I. Oostra, B.A. Hagemeijer, A. Bootsma, D. Hoeijmakers, J.H.J. |
1992-01-01
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RAD25(SSL2), a yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.
(Article)
Park, E. Guzder, S.N. Koken, M.H.M. Jaspers-Dekker, I. Weeda, G. Hoeijmakers, J.H.J. Prakash, S. Prakash, L. |
1992-01-01
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Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation group B correcting gene, ERCC3.
(Article)
Koken, M.H.M. Vreeken, C. Bol, S.A.M. Cheng, N.C. Jaspers-Dekker, I. Hoeijmakers, J.H.J. Eeken, J.C.J. Weeda, G. Pastink, A. |
1992-01-01
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DHR6, a Drosophila homolog of the yeast DNA repair gene RAD6.
(Article)
Koken, M.H.M. Reynolds, P. Bootsma, D. Hoeijmakers, J.H.J. Prakash, S. Prakash, L. |
1991-01-01
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Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.
(Article)
Koken, M.H.M. Reynolds, P. Jaspers-Dekker, I. Prakash, L. Prakash, S. Bootsma, D. Hoeijmakers, J.H.J. |
1991-01-01
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