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dai: 073935239
scopus: 7004899987
Kanaar, R.
(Roland Kanaar)Supervisor (promotor) of 7 dissertations
protein repair recombination damage rad 51 figure replication rad 54 dna damage activity molecule lament strand binding formation result pathway structure reaction mouse analysis response ssdna experiment mre 11 function dsdna presence complex yeast substrate number wild-type dna repair cerevisiae double-strand chromosome atp hydrolysis radiation interaction exchange kanaar antibody chromatin control es cells sequence cycle break treatment cancer rad 51 fi length checkpoint domain irradiation chromosomal expression level fibulin hydrolysis effect disassembly strand exchange region dna molecules filament sensitivity atpase image dsb repair acids research phase polymerase mutation dna replication mechanism dissociation nucleoprotein histone
10 Most Recent Publications
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Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks
(Article)
Levy-Barda, A. Lerenthal, Y. Ziv, Y. Shiloh, Y. Davis, A.J. Chung, Y. Essers, J. Shao, Z. Vliet, N. van Chen, D.J. Hu, M.C.-T. Kanaar, R. |
2011-12-15
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Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum
(Article)
Tanori, M. Pasquali, E. Mancuso, M. Saran, A. Pazzaglia, S. Leonardi, S. Giardullo, P. Majo, V. di Taccioli, G. Essers, J. Kanaar, R. Mullenders, L.H. Atkinson, M.J. |
2011-11-24
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The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination
(Article)
Eppink, B. Tafel, A.A. Hanada, K. Drunen, E. van Hickson, I.D. Essers, J. Kanaar, R. |
2011-11-10
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Mre11-Rad50 complex crystals suggest molecular calisthenics
(Article)
Wyman, C. Lebbink, J.H.G. Kanaar, R. |
2011-10-10
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Type i interferons as radiosensitisers for pancreatic cancer
(Article)
Morak, M.J.M. Koetsveld, P.M. van Kanaar, R. Hofland, L.J. Eijck, C.H.J. van |
2011-09-01
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Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques
(Article)
Holthausen, J.T. loenhout, M.T.J. van Sanchez, H. Ristic, D. Rossum-Fikkert, S.E. van Modesti, M. Dekker, C. Kanaar, R. Wyman, C. |
2011-08-01
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Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition
(Article)
Krawczyk, P.M. Eppink, B. Soullié, T. Rens, J.A.P. Verhagen, H.J.M. O'Connor, M.J. Frankene, N.A.P. Hagen, T.L.M. ten Kanaar, R. Aten, J.A. Essers, J. Stap, J. Rodermond, H. Odijk, H. Zelensky, A. Bree, C. van Stalpers, L.J. Buist, M.R. |
2011-06-14
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Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
(Article)
Moyal, L. Lerenthal, Y. Shkedy, D. Smorodinsky, N. Vliet, N. van Kuster, B. Mann, M. Ciechanover, A. Dahm-Daphi, J. Kanaar, R. Hu, M.-T. Chen, D.J. Gana-Weisz, M. Oren, M. Shiloh, Y. Mass, G. So, S. Wang, S-Y. Eppink, B. Chung, Y. Shalev, G. Shema, E. |
2011-04-08
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ATP-dependent and independent functions of Rad54 in genome maintenance
(Article)
Agarwal, S. Cappellen, W.A. van Guénolé, A. Eppink, B. Linsen, S.E.V. Meijering, E. Houtsmuller, A. Kanaar, R. Essers, J. |
2011-03-07
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Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
(Article)
Moyal, L. Lerenthal, Y. Shkedy, D. Smorodinsky, N. Vliet, N. van Kuster, B. Mann, M. Ciechanover, A. Dahm-Daphi, J. Kanaar, R. Hu, M.-T. Chen, D.J. Gana-Weisz, M. Oren, M. Shiloh, Y. Mass, G. So, S. Wang, S-Y. Eppink, B. Chung, Y. Shalev, G. Shema, E. |
2011-03-04
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