Machicao, F.

insulin secretion igf-i glucose-stimulated insulin secretion insulin secretion glucose subject diabetes study igf-ii type 2 diabetes genotype variant level netherland growth insulin sensitivity polymorphism glucose-stimulated cohort table group factor germany hyperglycemic clamps 192- bp allele glucose tolerance hyperglycemic gene variants sensitivity igf-ii gene variant population receptor tolerance igf-i gene study center igt groups igt subjects analysis center insulin sensitivity index 0.1 second-phase insulin secretion carrier change index association length birth weight dutch dutch ngt type 2 apai polymorphism weight glucose homeostasis allele igf-ii gene fasting defect 0.01 pancreatic result clamp insulin-like noncarrier development interquartile range igf-i promoter pancreatic beta cells promoter german ngt subjects igf-ii genes insulin action disposition index insulin levels glucose tolerance test trend igf genes van duijn cm pmol /l isi