Stam, R.W.

infant leukemia expression patient ara-c flt 3 sample lymphoblastic leukemia resistance study lymphoblastic mutation blood children leukemic level cancer infant mll figure sensitivity childhood leukemic cells treatment group kinase mll gene rearrangement pkc 412 flt 3 expression chapter protein mll gene rearrangements myeloid leukemia mrna expression inhibitor ara-c sensitivity drug resistance receptor infant mll patients nucleoside analysis activation infant mll samples domain myeloid non-infant pieter result value infant mll cells cytotoxicity translocation flt 3 gene transporter mll rearrangements ara-ctp flt 3 inhibition den boer ml factor wild-type inhibition presence difference concentration target sequence enzyme tyrosine gene expression flt 3 mutations mrna expression levels pieters r ara-c cytotoxicity netherland number table outcome activity probe membrane