Sallan, S.E.

infant patient expression leukemia prednisolone sample flt 3 blood .001 study resistance protein glucocorticoid pkc 412 prednisolone exposure level response leukemic apoptosi lymphoblastic leukemia mutation mll-rearranged kinase figure prednisolone resistance lymphoblastic noninfant prednisone flt 3 expression infant mll samples exposure infant mll patients children erasmus mc receptor mll-rearranged infant group glucocorticoid-induced apoptosis gene expression leukemic cells 8 hours probe infant mll number analysis sensitivity inhibition up-regulated flt 3 phosphorylation germline mll genes activation inhibitor infant patients glucocorticoid resistance erasmu signi factor treatment flt 3 inhibition infant mll cells volume patient groups cancer wild-type flt 3 flt 3l expression vivo prednisone response den boer ml pathway hospital myeloid leukemia cytotoxic response tyrosine identi flt 3 gene childhood pieter transcription signature library prednisolone-responsive genes