Margrie, T.W.

neuron brain recording imaging activity technique two-photon neurosci cortex helmchen monitoring synaptic animal function brecht nature fiber method microscope microscopy fluorescence approach margrie motor electrode signal whole-cell whole-cell recordings analysis neuroscience protein stimulation system plasticity network extracellular layer challenge genetic image vivo imaging study institute lentiviral physiology brain regions vector novel resolution light excitation department single-unit calcium preparation october population delivery spike intracellular svoboda membrane patch trachtenberg two-photon excitation microstimulation techniques potential osten mouse sakmann microstimulation whisker monitoring activity science macroscopic level single-unit signals manipulation memory patch pipette structure