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influenza virus epitope donor response hla-a influenza virus hla-b target cells compound peptide target group clone frequency effect assay cytotoxic virus-specific concentration stimulation 1.0 proliferation t-cell immunol 37 c ctl response cytotoxic t lymphocytes r 10f bioactive compounds ctl activity ctlp frequency activity class strain 2.5 105 pbmc antibody control presence percentage bioactive variant hla-a 2-negative donors production result molecule chlorogenic acid infection np 418-426/1980 epitope ctl clone number study increase effector recognition sigma chlorogenic group iii ratio addition table 1/np clone protein immunity plate virol virus-infected resvir function 418-426/1980 antigen influenza virus epitopes 1.0 mg /ml ctl assay flow cytometry influenza virus-infected pbmc np 418-426 epitope 418-426/1972 phenotype mutation
3 Most Recent Publications
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In vitro effect of bioactive compounds on influenza virus specific B and T cell responses.
(Article)
Boon, A.C.M. Vos, A.P.H. Graus, Y.M.F. Rimmelzwaan, G.F. Osterhaus, A.D.M.E. |
2002-03-25
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The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype
(Article)
Boon, A.C.M. Mutsert, G. de Graus, Y.M.F. Fouchier, R.A.M. Sintnicolaas, K. Rimmelzwaan, G.F. Osterhaus, A.D.M.E. |
2002-01-01
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Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes
(Article)
Boon, A.C.M. Mutsert, G. de Graus, Y.M.F. Fouchier, R.A.M. Sintnicolaas, K. Rimmelzwaan, G.F. Osterhaus, A.D.M.E. |
2002-01-01
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