Bergink, S.

protein repair damage hr 23b ubiquitin dna damage ubiquitylation lesion xpc-gfp nucleotide excision repair histone dna repair excision nucleotide level binding factor chromatin hr 23a uv-induced function response figure degradation proteasome polymerase sugasawa hoeijmaker mechanism ligase genome yeast xeroderma pigmentosum inclusion group pathway tfiih panel transcription domain modification analysis fluorescence vermeulen chapter activity uv irradiation replication regulation mobility recognition process study expression nucleus target ddb 2 hr 23 proteins antibody accumulation irradiation substrate ner factors hanaoka rad 23 dna damage response affinity usp 3 xpc protein damage-induced synthesis effect enzyme interaction ubiquitylated nature masutani ubiquitin proteasome system cancer