View Author
patient tamoxifen cancer allele plasma study genotype cyp 2d polymorphism breast effect concentration activity cyp 2c treatment urine neutropenia cyp 2d genotype sample level tramadol breast cancer patients variant lithium heparinized plasma phenotype group disease cyp 2d polymorphisms metabolism analysis metabolite cytochrome method cyp 3a tamoxifen therapy tamoxifen treatment frequency inhibitor breast cancer imi dose requirement cyp 2c allele tumor therapy imi dose population cyp 2d inhibitors difference adjuvant requirement outcome metabolizer cyp 2d phenotype cyp 3a allele table imipramine result association netherland promoter score van der bol lectin breast cancer res haplotype dextromethorphan mbl levels status irinotecan state collection pharmacol carrier impact cyp 2d medication genotyping mannose-binding lectin o-demethylation value survival incidence
7 Most Recent Publications
|
The CYP2C19*2 genotype predicts tamoxifen treatment outcome in advanced breast cancer patients
(Article)
Schaik, R.H.N. van Kok, M. Span, P.N. Laarhoven, H.W.M. van Sleijfer, S. Foekens, J.A. Linn, S.C. Berns, E.M.J. Sweep, F.C.J. Vliet, M. van Fessem, M.A. van Meijer van Gelder, M.E. Seynaeve, C.M. Lindemans, J. Wesseling, J. Veer, L.J. van 't |
2011-08-01
|
|
Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry
(Article)
Loos, W.J. Graan, A-J.M. de Bruijn, P. de Schaik, R.H.N. van Fessem, M.A. van Lam, M.H. Mathijssen, R.H.J. Wiemer, E.A.C. |
2011-01-25
|
|
Effects of mannose-binding lectin polymorphisms on irinotecan-induced febrile neutropenia
(Article)
Bol, J.M. van der Jonge, M.J.A. de Schaik, R.H.N. van Sparreboom, A. Fessem, M.A. van Geijn, F.E. van de Daele, P.L.A. van Verweij, J. Sleijfer, S. Mathijssen, R.H.J. |
2010-10-01
|
|
The impact of CYP2D6-predicted phenotype on tamoxifen treatment outcome in patients with metastatic breast cancer
(Article)
Lammers, L.A. Matthijsen, R.H.J. Gelder, T. van Bijl, M.J. Graan, A-J.M. de Seynaeve, C.M. Fessem, M.A. van Berns, P.M.J.J. Vulto, A.G. Schaik, R.H.N. van |
2010-09-07
|
|
Postmenstrual age and CYP2D6 polymorphisms determine tramadol O-demethylation in critically ill neonates and infants
(Article)
Allegaert, K. Schaik, R.H.N. van Vermeersch, S. Verbesselt, R. Cossey, V. Vanhole, C. Fessem, M.A. van Hoon, J.N. de Anker, J.N. van den |
2008-06-01
|
|
Association of graded allele-specific changes in CYP2D6 function with imipramine dose requirement in a large group of depressed patients
(Article)
Schenk, P.W. Fessem, M.A. van Verploegh-Van Rij, S. Mathot, R.A.A. Gelder, T. van Vulto, A.G. Vliet, M. van Lindemans, J. Bruijn, J.A. Schaik, R.H.N. van |
2008-06-01
|
|
The CYP3A4*3 allele: is it really rare?
(Article)
Schaik, R.H.N. van Wildt, S.N. de Brosens, R. Fessem, M.A. van Anker, J.N. van den Lindemans, J. |
2001-01-01
|