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study association osteoarthritis allele control haplotype subject rotterdam knee oa university hip oa analysis effect table result rheum population research sample polymorphism frequency cohort hand oa netherland variant arthritis rotterdam study phenotype radiographic disc degeneration cartilage score genotype meta-analysi factor department disease garp study linkage family body mass index sibling genome-wide signi finition region women method spine heterogeneity knee osteoarthritis osteophyte bone mineral density meulenbelt degeneration joint model susceptibility number genet replication genetic center col 2a gene analyses oxford article estimate hip roa finite grade marker group leiden university leiden protein shape ficant radiograph kerkhof
10 Most Recent Publications
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Novel genetic variants associated with lumbar disc degeneration in northern Europeans: A meta-analysis of 4600 subjects
(Article)
Williams, F.M.K. Bansa, A.T. Menni, C. Kloppenburg, M. Slagboom, P.E. Hunter, D. MacGregor, A.J. Uitterlinden, A.G. Spector, T.D. Meurs, J.B.J. van Bell, J.T. Meulenbelt, I. Suri, P. Rivadeneira Ramirez, F. Sambrook, P.N. Hofman, A. Bierma-Zeinstra, S.M.A. |
2012-09-19
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Osteoarthritis Susceptibility Genes Influence the Association Between Hip Morphology and Osteoarthritis
(Article)
Waarsing, J.H. Kloppenburg, M. Slagboom, P.E. Kroon, H.M. Houwing-Duistermaat, J.J. Weinans, H.H. Meulenbelt, I. |
2011-05-01
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
(Article)
Panoutsopoulou, K. Southam, L. Deloukas, P. Doherty, M. McCaskie, A. Ollier, W.E.R. Ralston, S.H. Spector, T.D. Valdes, A.M. Wallis, G.A. Wilkinson, J.M. Battley, K. Elliott, K.S. Blackburn, H. Blanco, F.J. Bumpstead, S. Cupples, L.A. Day-Williams, A.G. Dixon, K. Esko, T. Evangelou, E. Felson, D. Gómez-Reino, J.J. Wrayner, N. Gonzalez, A. Gordon, A. Gwilliam, R. Halldorsson, B.V. Hauksson, V.B. Hofman, B. Hunt, S.E. Ioannidis, J.P.A. Ingvarsson, T. Jonsdottir, I. Zhai, G. Jonsson, H. Keen, R. Kerkhof, H.J.M. Kloppenburg, M. Koller, N. Lakenberg, N. Lane, N.E. Lee, A.T. Metspalu, A. Meulenbelt, I. Beazley, C. Nevitt, M.C. O'Neill, F. Parimi, N. Potter, S.C. Rego-Perez, I. Riancho, J.A. Sherburn, K. Slagboom, P.E. Stefansson, K. Styrkarsdottir, U. Thorleifsson, G. Sumillera, M. Swift, D. Thorsteinsdottir, U. Tsezou, A. Uitterlinden, A.G. Meurs, J.B.J. van Watkins, B. Wheeler, M. Mitchell, S. Zhu, Y. Arden, N.K. Zmuda, J.M. Zeggini, E. Loughlin, J. Carr, A.M. Chapman, K. |
2011-05-01
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Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
(Article)
Kerkhof, H.J.M. Doherty, M. Hart, D.J. Hofman, A. Javaid, K. Kerna, I. Kisand, K. Kloppenburg, M. Krasnokutsky, S. Maciewicz, R.A. Meulenbelt, I. Muir, K.R. Arden, N.K. Rivadeneira Ramirez, F. Samuels, J. Sezgin, M. Slagboom, E.P. Smith, A.J.P. Spector, T.D. Tamm, A. Uitterlinden, A.G. Wheeler, M. Zhai, G. Abramson, S.B. Zhang, W. Meurs, J.B.J. van Valdes, A.M. Attur, M. Bos, S.D. Cooper, C. Dennison, E.M. Doherty, S.A. Evangelou, E. |
2011-03-01
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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Doherty, S.A. Felson, D. Gonzalez, A. Gordon, A. Harilainen, A. Hart, D.J. Hauksson, V.B. Heliovaara, M. Hofman, A. Ikegawa, S. Akune, T. Ingvarsson, T. Jiang, Q. Jonsson, H. Jonsdottir, I. Kawaguchi, H. Kloppenburg, M. Kujala, U.M. Lane, N.E. Leino-Arjas, P. Lohmander, L.S. Arden, N.K. Luyten, F.P. Malizos, K.N. Nakajima, M. Nevitt, M.C. Pols, H.A.P. Rivadeneira Ramirez, F. Shi, D. Slagboom, E. Spector, T.D. Stefansson, K. Aromaa, A. Sudo, A. Tamm, A. Tamm, A.E. Tsezou, A. Uchida, A. Uitterlinden, A.G. Wilkinson, J.M. Yoshimura, N. Valdes, A.M. Meurs, J.B.J. van Bierma-Zeinstra, S.M.A. Carr, A.M. Cooper, C. Dai, J. Doherty, M. |
2011-03-01
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Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
(Article)
Evangelou, E. Valdes, A.M. Rayner, N.W. Southam, L. Zhai, G. Elliot, K.S. Hunt, S.E. Kerkhof, H.J.M. Styrkarsdottir, U. Zhu, Y. Meulenbelt, I. Lories, R.J. Karassa, F.B. Tylzanowski, P. Bos, S.D. |
2011-02-01
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Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: Results of a meta-analysis
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Spector, T.D. Stolk, L. Tsezou, A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Carr, A.M. Gonzalez, A. Hart, D.J. Hofman, A. Kloppenburg, M. Lane, N.E. Loughlin, J. Nevitt, M.C. |
2010-11-16
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Familial influence on tibiofemoral alignment
(Article)
Tufan, A. Meulenbelt, I. Bijsterbosch, J. Kroon, H.M. Bierma-Zeinstra, S.M.A. Nelissen, R.G.H.H. Kloppenburg, M. |
2010-03-01
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A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
(Article)
Kerkhof, H.J.M. Lories, R.J. Thorleifsson, G. Zhai, G. Zhang, F. Zhu, Y. Breggen, R. van der Carr, A.M. Doherty, M. Felson, D. Gonzalez, A. Halldorsson, B.V. Meulenbelt, I. Hart, D.J. Hauksson, V.B. Hofman, A. Ioannidis, J.P.A. Kloppenburg, M. Lane, N.E. Loughlin, J. Luyten, F.P. Nevitt, M.C. Parimi, N. Jonsdottir, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Styrkarsdottir, U. Tsezou, A. Putte, T. van de Zmuda, J. Spector, T.D. Zwart, J-A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Arp, P.P. Ingvarsson, T. Jhamai, M. Jonsson, H. Stolk, L. |
2010-02-01
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Interleukin-1 region meta-analysis with osteoarthritis phenotypes
(Article)
Moxley, G. Meulenbelt, I. Chapman, K. Diujn, C.M. van Eline Slagboom, P. Neale, M.C. Smith, A.J.P. Carr, A.M. Loughlin, J. |
2010-02-01
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