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erythroid globin expression differentiation factor protein transcription liver blood locus globin locus blood cells hemoglobin erythroid cells culture -/- mouse progenitors promoter chromatin erythrocyte control absence erythroid progenitors chapter binding beta-globin erythropoiesi grosveld grosveld f synthesis gene expression 12.5 region globin genes domain transcription factors terminal differentiation regulation number membrane e 12.5 result terminal eklf -/- liver cells adult eklf-dependent element analysis erythroid differentiation erythroid kruppel-like factor level hematopoietic study medium interaction globin gene transcriptional kruppel-like model wild-type presence program globin promoter frequency thalassemia function bieker deletion phenotype histone target embryo structure eklf -/- cells progenitor family mutation target genes
2 Most Recent Publications
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The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability.
(Article)
Drissen, R.P.M. Lindern, M.M. von Kolbus, A. Driegen, S. Steinlein, P. Beug, H. Grosveld, F.G. Philipsen, S. |
2005-06-01
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Regulation of Erythroid Gene Expression by the Transcription Factor EKLF
(Doctoral Thesis)
Drissen, R.P.M. |
2004-10-27
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