View Author
cgk ii mouse channel protein cgk i response transport membrane secretion resveratrol brosi epithelial activation physiol activity study fibrosis 508del conductance iec-cf 7 cells chloride lubiprostone fi brosis strain mutation tissue model kinase experiment disease autophosphorylation intestine airway jonge level effect epithelium phosphorylation patient forskolin efflux expression volume phenotype res -3-g miglustat presence 125 i efflux iec-cf substrate epithelial cells concentration cf patients analog peptide function control value cgmp analogs transmembrane result mrp 3 cf mice fl uid secretion metabolite / journal infection difference plasma animal erasmu solution background cf /3 mice vaandrager erasmus mc regulator f 508del secretory addition
10 Most Recent Publications
|
Mouse models of cystic fibrosis: Phenotypic analysis and research applications
(Article)
Wilke, M. Buijs-Offerman, R.M. Aarbiou, J. Colledge, W.H. Sheppard, D.N. Touqui, L. Bot, A.G. Jorna, H. Jonge, H. de Scholte, B.J. |
2011-07-01
|
|
Assessment of CFTR function in homozygous R117H-7T subjects
(Article)
Nooijer, R.A. de Nobel, J.M. Arets, H.G. Bot, A.G. Berkhout, F.T. van Rijke, Y.B. de Jonge, H. de Bronsveld, I. |
2011-04-20
|
|
Activation of Intestinal Cl- Secretion by Lubiprostone Requires the Cystic Fibrosis Transmembrane Conductance Regulator
(Article)
Bijvelds, M.J. Bot, A.G. Escher, J.C. Jonge, H.R. de |
2009-09-01
|
|
Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol
(Article)
Wetering, K. van de Burkon, A. Feddema, W. Bot, A.G. Jonge, H.R. de Somoza, V. Borst, P. |
2009-04-01
|
|
Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells
(Article)
Noël, S. Wilke, M. Bot, A.G. Jonge, H.R. de Becq, F. |
2008-06-01
|
|
Very mild disease phenotype of congenic CftrTgH(neoim)Hgu cystic fibrosis mice
(Article)
Tóth, B. Wilke, M. Jonge, H.R. de Hedrich, H.J. Breves, G. Tümmler, B. Stanke, F. Dorsch, M. Jansen, S. Wedekind, D. Charizopoulou, N. Bot, A.G. Burmester, M. Leonhard-Marek, S. |
2008-04-09
|
|
Osmosignaling and Volume Regulation in Intestinal Epithelial Cells
(Article)
Lim, C.H. Bot, A.G. Jonge, H.R. de Tilly, B.C. |
2007-12-01
|
|
Autophosphorylation of cGMP-dependent protein kinase type II.
(Article)
Vaandrager, A.B. Hogema, B.M. Jonge, H.R. de Edixhoven, M.J. Burg, C.M. van den Bot, A.G. Klatt, P. Ruth, P Hofmann, F. Damme, J. van Vandekerckhove, J. |
2003-08-01
|
|
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation
(Article)
Vaandrager, A.B. Smolenski, A. Tilly, B.C. Houtsmuller, A.B. Ehlert, E.M.E. Bot, A.G. Edixhoven, M.J. Boomaars, W.E. Lohmann, S.M. Jonge, H.R. de |
1998-01-01
|
|
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta
(Article)
Vaandrager, A.B. Lohmann, S.M. Jarchau, T. Walter, U. Jonge, H.R. de Poller, W.C. Tilly, B.C. Smolenski, A. Schneider-Rasp, S. Bot, A.G. Edixhoven, M.J. Scholte, B.J. |
1997-01-01
|
