Wang, S-Y.

chromosome disease patient alzheimer chromosome 14 mutation early-onset analysis polymorphism sequence dlst gene ad patients early-onset alzheimer e 2k component region family ad /b families ad /a van broeckhoven intron ad 3 gene candidate sscp analysis exons 8 pcr products onset broeckhoven dehydrogenase table linkage genet kgdhc sequencing variation mapping b -2610 antwerpen sscp patterns dihydrolipoyl succinyltransferase gene onset age mutation analysis locus 49 ad patients early-onset ad promoter region disease locus martin succinyltransferase age 55 years primer yac contig map primers neuroscience letter dihydrolipoyl promoter 73-77 component research neurology university brain belgium position ad cases backhoven pcr sequencing sequence variations product protein genomic c-fos gene kgdhc activity science a-ketoglutarate dehydrogenase population-based study netherland genomic dna marker 55 years 15 exons