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study association osteoarthritis control allele haplotype effect rotterdam university knee oa subject hip oa women analysis radiographic table polymorphism rotterdam study population frequency hand oa rheum arthritis result sample genotype variant research genome-wide phenotype replication cartilage meta-analysi oxford genetic garp study difference radiographic oa linkage heterogeneity analyses marker method receptor genet ␣ gene score susceptibility expression signi esr 2 gene estrogen patient knee osteoarthritis netherland model cohort disease figure value region summary evidence panel ratio department rs 7775 gdf 5 factor radiographic knee oa center japanese chondrocyte ptgs 2 k /l score signal oa phenotypes osteoporotic fractures meulenbelt grade
9 Most Recent Publications
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A variant in MCF2L is associated with osteoarthritis
(Article)
Day-Williams, A.G. Southam, L. Keis, A. Kerkhof, H.J.M. Thorleifsson, G. Arden, N.K. Carr, A. Chapman, K. Deloukas, P. Loughlin, J. McCaskie, A. Ollier, W.E.R. Panoutsopoulou, K. Ralston, S.H. Spector, T.D. Wallis, G.A. Wilkinson, J.M. Aslam, N. Birell, F. Carluke, I. Joseph, J. Rai, A. Reed, M. Rayner, N.W. Walker, K. Doherty, S.A. Jonsdottir, I. Maciewicz, R.A. Muir, K.R. Metspalu, A. Rivadeneira Ramirez, F. Stefansson, K. Styrkarsdottir, U. Uitterlinden, A.G. Esko, T. Meurs, J.B.J. van Zhang, W. Valdes, A.M. Zeggini, E. Estrada Gil, J.K. Helgadottir, H.T. Hofman, A. Ingvarsson, T. Jonsson, H. |
2011-09-09
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
(Article)
Panoutsopoulou, K. Southam, L. Deloukas, P. Doherty, M. McCaskie, A. Ollier, W.E.R. Ralston, S.H. Spector, T.D. Valdes, A.M. Wallis, G.A. Wilkinson, J.M. Battley, K. Elliott, K.S. Blackburn, H. Blanco, F.J. Bumpstead, S. Cupples, L.A. Day-Williams, A.G. Dixon, K. Esko, T. Evangelou, E. Felson, D. Gómez-Reino, J.J. Wrayner, N. Gonzalez, A. Gordon, A. Gwilliam, R. Halldorsson, B.V. Hauksson, V.B. Hofman, B. Hunt, S.E. Ioannidis, J.P.A. Ingvarsson, T. Jonsdottir, I. Zhai, G. Jonsson, H. Keen, R. Kerkhof, H.J.M. Kloppenburg, M. Koller, N. Lakenberg, N. Lane, N.E. Lee, A.T. Metspalu, A. Meulenbelt, I. Beazley, C. Nevitt, M.C. O'Neill, F. Parimi, N. Potter, S.C. Rego-Perez, I. Riancho, J.A. Sherburn, K. Slagboom, P.E. Stefansson, K. Styrkarsdottir, U. Thorleifsson, G. Sumillera, M. Swift, D. Thorsteinsdottir, U. Tsezou, A. Uitterlinden, A.G. Meurs, J.B.J. van Watkins, B. Wheeler, M. Mitchell, S. Zhu, Y. Arden, N.K. Zmuda, J.M. Zeggini, E. Loughlin, J. Carr, A.M. Chapman, K. |
2011-05-01
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Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: Results of a meta-analysis
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Spector, T.D. Stolk, L. Tsezou, A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Carr, A.M. Gonzalez, A. Hart, D.J. Hofman, A. Kloppenburg, M. Lane, N.E. Loughlin, J. Nevitt, M.C. |
2010-11-16
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A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
(Article)
Kerkhof, H.J.M. Lories, R.J. Thorleifsson, G. Zhai, G. Zhang, F. Zhu, Y. Breggen, R. van der Carr, A.M. Doherty, M. Felson, D. Gonzalez, A. Halldorsson, B.V. Meulenbelt, I. Hart, D.J. Hauksson, V.B. Hofman, A. Ioannidis, J.P.A. Kloppenburg, M. Lane, N.E. Loughlin, J. Luyten, F.P. Nevitt, M.C. Parimi, N. Jonsdottir, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Styrkarsdottir, U. Tsezou, A. Putte, T. van de Zmuda, J. Spector, T.D. Zwart, J-A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Arp, P.P. Ingvarsson, T. Jhamai, M. Jonsson, H. Stolk, L. |
2010-02-01
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Interleukin-1 region meta-analysis with osteoarthritis phenotypes
(Article)
Moxley, G. Meulenbelt, I. Chapman, K. Diujn, C.M. van Eline Slagboom, P. Neale, M.C. Smith, A.J.P. Carr, A.M. Loughlin, J. |
2010-02-01
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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
(Article)
Evangelou, E. Chapman, K. Hauksson, V.B. Hofman, A. Hart, D.J. Ikegawa, S. Ingvarsson, T. Jiang, Q. Jonsdottir, I. Jonsson, H. Kerkhof, H.J.M. Kloppenburg, M. Meulenbelt, I. Lane, N.E. Li, J. Lories, R.J. Meurs, J.B.J. van Näkki, A. Nevitt, M.C. Rodriguez-Lopez, J. Shi, D. Slagboom, P.E. Zwart, J-A. Karassa, F.B. Tsezou, A. Wallis, G.A. Watson, C.M. Spector, T.D. Uitterlinden, A.G. Valdes, A.M. Ioannidis, J.P.A. Loughlin, J. Carr, A.M. Doherty, M. Gómez-Reino, J.J. Gonzalez, A. Halldorsson, B.V. |
2009-06-01
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Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis
(Article)
Meulenbelt, I. Min, J. Meurs, J.B.J. van Deure, W.M. van der Visser, T.J. Seymour, A.B. Lakenberg, N. Breggen, R. van der Kremer, D. Tikka-Kleemola, P. Kloppenburg, M. Loughlin, J. Bos, S.D. Slagboom, P.E. Riyazi, N. Houwing-Duistermaat, J.J. wijk, H.J. van der Kroon, H.M. Nakajima, M. Ikegawa, S. Uitterlinden, A.G. |
2008-06-15
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Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis
(Article)
Valdes, A.M. Loughlin, J. Abkevich, V. Ge, D. Hofman, A. Uitterlinden, A.G. Hart, D.J. Zhang, F. Zhai, G. Egli, R.J. Lanchbury, J. Spector, T.D. Timms, K.M. Meurs, J.J.B. van Southam, L. Wilson, S.G. Doherty, S. Lories, R.J. Luyten, F.P. Gutin, A. |
2008-06-06
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Estrogen receptor and gene haplotype is associated with radiographic osteoarthritis of the knee in the elderly men and woman
(Article)
Bergink, A.P. Loughlin, J. Arp, P.P. Fang, Y. Hofman, A. Leeuwen, J.P.T.M. van Duijn, C.M. van Uitterlinden, A.G. Pols, H.A.P. Meurs, J.B.J. van |
2003-07-01
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