Kobayashi, K.

activity mouse extract nicking activity repair protein nicking cry 1 glycosylase fraction wild-type clock mnth 1 figure ap lyase activity tgg 1 endonuclease circadian cry 2 mitochondrial light oxidative dna damage mnth 1 gene substrate damage analysis tgg 2 fraction buffer liver oxidative cry proteins ±/± column 5¢- blot analysis science novel escherichia 0.1 m nacl photoreceptor ap endonuclease activity mitochondrial extracts mitochondria university fragment rhythm product excision genomic mnth 1 ±/± figure 1 dna damage base excision repair oxidative damage disruption wild-type mouse -3¢ buffer k tgg 2 activity mouse liver tg substrate glycol tgg 1 activity nicking activities amount lyase endoiii assay figure 6 photolyase 8- oxog function genomic dna system double-mutant period escherichia coli nature result thymine