Kazemier, K.M.

patient leukemia resistance lymphoblastic leukemia expression level prednisolone score treatment childhood lymphoblastic drug resistance l-asparaginase study blood children leukemic cells protein response leukemic figure peg-asparaginase group pva score apoptosi procaspase caspase sensitivity apoptotic cancer sample pieters r vincristine 2- dg pieter outcome glucose analysis table result asparagine asparaginase therapy activation caspase -3 activation survival glucocorticoid induction coall daunorubicin glucocorticoid resistance ps externalization glycolysi relapse effect intracellular peg-asparaginase im appel apoptotic parameters procaspase -2 expression b-lineage number probe factor parameter control correlation profile value parp expression protocol den boer ml vivo response prednisolone resistance window prognostic diagnosis exposure copyright 2004 massachusetts t-lineage erasmu