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scopus: 7005856145

Boersma, A.W.M.

(Anton Boersma)


cisplatin resistance yeast expression cancer sensitivity platinum cerevisiae accumulation doxorubicin strain mirna oxaliplatin marker hslc 22a protein sky 1 assay cisplatin resistance npr 2⌬ cells disruption blood npr 2 srpk 1 imatinib sky 1 cells sky 1 gene uptake netherland body fluids mirna markers platinum compounds phenotype fluid concentration agent control study schenk transporter microarray rt-pcr 293/neo burger saccharomyces cerevisiae result sample mechanism hek 293/hslc cells compound figure repair mutation anticancer saccharomyce kinase isogenic semen 2780 cells experiment carboplatin 293/hslc sky 1p level taqman treatment cisplatin-resistant medium substrate mgsc-sky 1 cells doxorubicin resistance transport mgsc-sky npr 2 gene intracellular cancer cell lines mir -891a cisplatin sensitivity analysis drug resistance




6 Most Recent Publications

MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation (Article)
Zubakov, D. Boersma, A.W.M. Choi, Y. Kuijk, P.F. van Wiemer, E.A.C. Kayser, M.
2010-05-01
Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2) (Article)
Burger, H. Zoumaro-Djayoon, A. Boersma, A.W.M. Helleman, J. Berns, P.M.J.J. Mathijssen, R.H.J. Loos, W.J. Wiemer, E.A.C.
2010-02-01
Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump (Article)
Burger, H. Tol, H. van Boersma, A.W.M. Brok, M. Wiemer, E.A.C. Stoter, G. Nooter, K.
2004-01-01
Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill. (Article)
Schenk, P.W. Brok, M. Boersma, A.W.M. Brandsma, J.A. Dulk, H. den Burger, H. Stoter, G. Brouwer, J. Nooter, K.
2003-08-01
Inactivation of the Saccharomyces cerevisiae SKY1 gene induces a specific modification of the yeast anticancer drug sensitivity profile accompanied by a mutator phenotype (Article)
Schenk, P.W. Boersma, A.W.M. Brok, M. Burger, H. Stoter, G. Nooter, K.
2002-01-01
SKY1 is involved in cisplatin-induced cell kill in Saccharomyces cerevisiae, and inactivation of its human homologue, SRPK1, induces cisplatin resistance in a human ovarian carcinoma cell line (Article)
Schenk, P.W. Boersma, A.W.M. Brandsma, J.A. Dulk, H. den Burger, H. Stoter, G. Brouwer, J. Nooter, K.
2001-01-01