Schiffelers, R.M.

(Raymond Schiffelers)

liposomes infection treatment liposome localization survival study result agent blood concentration gentamicin aminoglycoside tissue pneumoniae circulation model le-gen effect liposomal antibiotic lipid efficacy 5 days bacteria delivery amikacin antimicrobial injection target number storm interaction inoculation strain bakker-woudenberg combination formulation figure chapter storm g animal pneumonia host defense antimicrobial agents leukopenic rats chemother administration antimicrob carrier drug delivery capillary permeability addition circulation time particle size target site system increase defense ef ﬁcacy degree bilayer patient encapsulated ceftazidime leukopenic distribution circulation kinetics release klebsiella right lung liposome localization activity permeability ssl localization sterically kinetic woodle uptake mycobacterium

5 Most Recent Publications

Targeted drug delivery to enhance efficacy and shorten treatment duration in disseminated Mycobacterium avium infection in mice (Article) Steenwinkel, J.E.M. de Vianen, W. van Kate, M.T. ten Verbrugh, H.A. Agtmael, M.A. van Schiffelers, R.M. Bakker-Woudenberg, I.A.J.M.	2007-11-01
Therapeutic efficacy of liposome-encapsulated gentamicin in rat Klebsiella pneumoniae pneumonia in relation to impaired host defense and low bacterial susceptibility to gentamicin. (Article) Schiffelers, R.M. Storm, G. Kate, M.T. ten Bakker-Woudenberg, I.A.J.M.	2001-02-08
Liposomal targeting of antimicrobial agents to bacterial infections (Doctoral Thesis) Schiffelers, R.M.	2001-02-07
In vivo synergistic interaction of liposome-coencapsulated gentamicin and ceftazidime (Article) Schiffelers, R.M. Storm, G. Kate, M.T. ten Stearne-Cullen, L.E. Hollander, J.G. den Verbrugh, H.A. Bakker-Woudenberg, I.A.J.M.	2001-01-01
Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies (Article) Schiffelers, R.M. Storm, G. Bakker-Woudenberg, I.A.J.M.	2001-01-01

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