Stearne-Cullen, L.E.

treatment survival infection leukopenic rats agent liposomes efficacy amb desoxycholate leukopenic amb /kg peg-amb-lip concentration interaction pneumoniae inoculation fumigatu aspergillosi amphotericin combination strain model result desoxycholate liposomal blood chemother study antimicrob effect number agents chemother antibiotic right lung fumigatus inoculation animal lipid ambisome leukocyte liver amphotericin b 10 mg administration dissemination bacteria 15/15 liposomal amphotericin b ceftazidime bakker-woudenberg antimicrobial right le-gn placebo treatment synergy antimicrobial agents rat model curve tissue netherland placebo le-cz death patient iso-effective doses drug interaction /or cz drug interactions rat survival 14 mg gentamicin 10- day treatment agent b incubation formulation pneumoniae strain time-kill curves delivery schiffeler pneumonia amb-lipid formulations 1998.