View Author
scopus: 6505930643

Geelhoed-Mieras, M.M.

(Martina Geelhoed-Mieras)


virus fluenza infection group response epitope vaccine influenza fluenza virus vaccination immunity antibody t-cell heterosubtypic immunity virus-speci /h virus children vaccinated heterosubtypic fluenza viruses hla-b study virol assay speci weight titer cytotoxic pandemic weight loss peptide protection rimmelzwaan substitution virus titers signi inoculation strain wiv nibrg -14 cytotoxic t lymphocytes number control induction c 57bl mice iav hk /68 osterhau bodewe covaccinehttm animal variant netherland influenza virus clone /34-np presence antigen recognition fi tness difference covaccine ht *2705 immunol lymphocytes result nibrg iav ind /05 challenge unvaccinated /h viruses sequence effect body weight -14 protein signi ficant differences staining acid substitutions percentage virus-specific signi ficantly




10 Most Recent Publications

Annual influenza vaccination affects the development of heterosubtypic immunity (Article)
Bodewes, R. Fraaij, P.L.A. Kreijtz, J.H.C.M. Geelhoed-Mieras, M.M. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2012-12-07
Annual vaccination against influenza virus hampers development of virus-specific CD8 + T cell immunity in children (Article)
Bodewes, R. Fraaij, P.L.A. Geelhoed-Mieras, M.M. Baalen, C.A. van Tiddens, H.A.W.M. Rossum, A.M.C. van Klis, F.R. van der Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2011-11-01
Cross-protective immunity against influenza pH1N1 2009 viruses induced by seasonal influenza A (H3N2) virus is mediated by virus-specific T-cells (Article)
Hillaire, M.L.B. Trierum, S.E. Kreijtz, J.H.C.M. Bodewes, R. Geelhoed-Mieras, M.M. Nieuwkoop, N. Fouchier, R.A.M. Kuiken, T. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2011-10-01
Vaccination against seasonal influenza A/H3N2 virus reduces the induction of heterosubtypic immunity against influenza A/H5N1 virus infection in ferrets (Article)
Bodewes, R. Kreijtz, J.H.C.M. Geelhoed-Mieras, M.M. Amerongen, G. van Verburgh, R.J. Trierum, S.E. Kuiken, T. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2011-03-01
Redundancy of the influenza A virus-specific cytotoxic T lymphocyte response in HLA-B*2705 transgenic mice limits the impact of a mutation in the immunodominant NP383-391 epitope on influenza pathogenesis (Article)
Bodewes, R. Geelhoed-Mieras, M.M. Nieuwkoop, N. Hanson, J.A. David, C.S. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2011-01-01
A single immunization with covaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets (Article)
Bodewes, R. Kreijtz, J.H.C.M. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F. Amerongen, G. van Geelhoed-Mieras, M.M. Verburgh, R.J. Heldens, J.G.M. Bedwell, J. Brand, J.M.A. van den Kuiken, T. Baalen, C.A. van
2010-08-01
Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice (Article)
Bodewes, R. Kreijtz, J.H.C.M. Hillaire, M.L.B. Geelhoed-Mieras, M.M. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2010-07-01
The novel adjuvant CoVaccineHT™ increases the immunogenicity of cell-culture derived influenza A/H5N1 vaccine and induces the maturation of murine and human dendritic cells in vitro (Article)
Bodewes, R. Geelhoed-Mieras, M.M. Heldens, J.G.M. Glover, J. Lambrecht, B.N.M. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2009-11-16
Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus (Article)
Bodewes, R. Kreijtz, J.H.C.M. Baas, C. Geelhoed-Mieras, M.M. Mutsert, G. de Amerongen, G. van Brand, J.M.A. van den Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2009-05-14
An amino acid substitution in the influenza A virus hemagglutinin associated with escape from recognition by human virus-specific CD4+ T-cells (Article)
Berkhoff, E.G.M. Geelhoed-Mieras, M.M. Jonges, M. Smith, D.J. Fouchier, R.A.M. Osterhaus, A.D.M.E. Rimmelzwaan, G.F.
2007-06-01