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Spits, H.

(Hergen Spits)


il -7 expression t cells blood thymocyte number development lti cells transplantation t-cell marrow lymphoid thymopoiesi thymic analysis recovery balb-rag immunol murine lymph spleen b cells flow cytometry cd 56+cd cells effect lin –cd cells receptor cytokine 56+cd mouse lti-like pja-bp population expansion donor thymu anti-cd cytometry progenitors pja-bp expression hematopoietic liver result cnk cells interleukin subset graft differentiation frequency experiment rejection figure organ huil -7 level progenitor 127+ lymph nodes cell transplantation bone marrow transplantation bone marrow administration control model tissue il -22 tonsil il -17 precursor downloaded cd 127 clone t cell development lineage study treatment factor recipient immunology increase




9 Most Recent Publications

Stem cell factor consistently improves thymopoiesis after experimental transplantation of murine or human hematopoietic stem cells in immunodeficient mice (Article)
Wils, E-J. Rombouts, E.J.C. Mourik, I. van Spits, H. Legrand, N. Braakman, E. Cornelissen, J.J.
2011-09-15
Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells (Article)
Crellin, N.K. Trifari, S. Kaplan, C.D. Cupedo, T. Spits, H.
2010-02-15
IL-7 enhances thymic human T cell development in "human immune system" Rag2-/-IL-2Rγc-/- mice without affecting peripheral T cell homeostasis (Article)
Lent, A.U. van Dontje, W. Santo, J.P. di Spits, H. Legrand, N. Nagasawa, M. Siamari, R. Bakker, A.Q. Pouw, S.M. Maijoor, K.A. Weijer, K. Cornelissen, J.J. Blom, B.
2009-12-15
Interleukin-22-producing innate immune cells: New players in mucosal immunity and tissue repair? (Article)
Vivier, E. Spits, H. Cupedo, T.
2009-04-01
T cell-independent development and induction of somatic hypermutation in human IgM+IgD+CD27+ B cells (Article)
Scheeren, F.A. Nagasawa, M. Weijer, K. Cupedo, T. Kirberg, J. Legrand, N. Spits, H.
2008-09-01
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells (Article)
Cupedo, T. Crellin, N.K. Papazian, N. Rombouts, E.J. Weijer, K. Grogan, J.L. Fibbe, W.E. Cornelissen, J.J. Spits, H.
2008-01-01
IL-7 mediated protection against minor antigen-mismatched allograft rejection is associated with enhanced recovery of regulatory T cells (Article)
Broers, A.E.C. Bruinsma, M. Posthumus-van Sluijs, S.J. Wils, E-J. Spits, H. Löwenberg, B. Braakman, E. Cornelissen, J.J.
2007-08-01
Interleukin-7 improves T-cell recovery after experimental T-cell-depleted bone marrow transplantation in T-cell-deficient mice by strong expansion of recent thymic emigrants (Article)
Broers, A.E.C. Posthumus-van Sluijs, S.J. Spits, H. Holt, B. van der Löwenberg, B. Braakman, E. Cornelissen, J.J.
2003-01-01
PJA-BP expression and TCR delta deletion during human T cell differentiation (Article)
Verschuren, M.C.M. Blom, B. Bogers, A.J.J.C. Spits, H. Dongen, J.J.M. van
1998-01-01