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patient expression ms patients lymph nodes lymph monocyte control macrophage sclerosis disease type 1 myelin cns-draining lymph nodes antigen immunol pregnancy study adhesion level myelin-laden macrophages il -7 stimulation brain netherland receptor signi lesion t cells protein myelin-laden blood erasmu biozzi abh mice frequency c 57bl mice result trimester mrp -8/14 model il -7 erasmus univ rotterdam response increase subset antigen-containing cells -8/14 cns-draining antibody diabetes molecule myelin ingestion stimulation number control subjects signi ficant increase cns antigens rotterdam relapse women ccr 7 chemokine analysis system il -7ra damage t-cell proliferation serum type 2 pstat dendritic cells biozzi library erasmus mc encephalomyeliti difference erasmus mc antigen-containing eae-affected ficant animal cd 11b
9 Most Recent Publications
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The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis
(Article)
Kreft, K.L. Verbraak, E. Wierenga-Wolf, A.F. Meurs, M. van Oostra, B.A. Laman, J.D. Hintzen, R.Q. |
2012-02-15
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Myelin ingestion alters macrophage antigen-presenting function in vitro and in vivo
(Article)
Zwam, M. van Samsom, J.N. Laman, J.D. Nieuwenhuis, E.E.S. Melief, M.J. Wierenga-Wolf, A.F. Dijke, I.E. Talens, S. Meurs, M. van Voerman, J.S. Boven, L.A. |
2011-07-01
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The monocyte transcriptome during pregnancy in multiple sclerosis: Prominent expression of the Fc-receptor CD64
(Article)
Neuteboom, R.F. Verbraak, E. Hintzen, R.Q. Wierenga-Wolf, A.F. Voerman, J.S. Meurs, M. van Swagemakers, S.M.A. Spek, P.J. van der Steegers-Theunissen, R.P.M. Groot, C.J.M. de Laman, J.D. |
2011-04-01
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Role of CD8 regulatory T-cells in multiple sclerosis
(Article)
Kreft, K.L. Verbraak, E. Wierenga-Wolf, A.F. Laman, J.D. Hintzen, R.Q. |
2011-03-01
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Pregnancy-induced fluctuations in functional T-cell subsets in multiple sclerosis patients
(Article)
Neuteboom, R.F. Verbraak, E. Wierenga-Wolf, A.F. Meurs, M. van Steegers-Theunissen, R.P.M. Groot, C.J.M. de Laman, J.D. Hintzen, R.Q. |
2010-09-01
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Myelin ingestion by macrophages promotes their motility and capacity to recruit myeloid cells
(Article)
Zwam, M. van Wierenga-Wolf, A.F. Melief, M.J. Schrijver, B. Laman, J.D. Boven, L.A. |
2010-08-01
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Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
(Article)
Zwam, M. van Huizinga, R. Laman, J.D. Heijmans, N. Meurs, M. van Wierenga-Wolf, A.F. Melief, M.J. Hintzen, R.Q. Hart, B.A.T. Amor, S. Boven, L.A. |
2009-03-01
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Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE
(Article)
Zwam, M. van Huizinga, R. Bechmann, I. Hintzen, R.Q. Hart, B. 't Amor, S. Laman, J.D. Boven, L.A. Melief, M.J. Wierenga-Wolf, A.F. Meurs, M. van Voerman, J.S. Biber, K.P.H. Boddeke, H.W.G.M. Höpken, U.E. Meisel, C. |
2009-03-01
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Increased serum levels of MRP-8/14 in type 1 diabetes induce an increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin
(Article)
Bouma, G. Lam-Tse, W.K. Wierenga-Wolf, A.F. Drexhage, H.A. Versnel, M.A. |
2004-01-01
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