Thompson, D.

cancer breast cancer brca 1 brca 2 mutations breast chek 2*1100delc family mutation individual 2*1100delc chek 2 control variant frequency breast cancer risk genetic carrier brca 2 netherland analysis breast cancer unselected nature research susceptibility allele group chromosome marker linkage 1100 delc mutation breast cancer susceptibility study chek 2*1100delc variant population control individuals fi rst series heteroduplex analysis segregation estimate analyses model america li-fraumeni syndrome prevalence women phosphorylate chromosome 22 q table family history chromosome 22 cancer research uk institute lod scores breast cancer incidence score genomic coding sequence sequence population-based series noncarrier family eur 60 cancer res chk 2 kinase letter germany effect genome damage syndrome protein evidence volume <60 checkpoint hospital publishing haplotype population-based