Rooijen van, N.

macrophage antigen response iscom virus animal liposomes rv-bpl rabie rabies virus antigen splenic spleen splenic macrophages claassen localization clodronate study clodronate liposomes depletion rv-iscom presentation immunol van rooijen n immunization zone macrophages rooijen rabies virus protein uptake t-cell humoral claassen e science immunology decrease antibody pattern t cells system induction liposome effect dendritic elimination treatment room temperature class humoral response localization patterns serum t-cell responses cytotoxic t lymphocytes antibody responses macrophage depletion metallophilic macrophages proliferative t-cell responses rabies virus iscom clodronate liposome treatment method elisa result blackwell localization pattern osterhau 455-460 adjuvant control cytotoxic filter vaccine difference removal technique dendritic cells huang l pathway pulp macrophages reticuloendothelial system formulation netherland