View Author
scopus: 8872832700

Smit, P.

(Pauline Smit)


level study glucocorticoid polymorphism expression receptor cortisol patient effect assay sensitivity carrier endocrinol gc sensitivity metab response dehydrogenase variant activity blood serum group subject glucocorticoid receptor gene control allele concentration result chapter rotterdam study difference number hydrocortisone glucose glucocorticoid receptor increase koper jw resistance il -2 n 363s polymorphism blood pressure 22/23ek protein analysis koper rotterdam cyp 3a polymorphism c 3435t population lambert genotype body composition 11- regulation transcription factor transactivation transrepression 3435t jong fh body mass index androgen androstenedione metabolism sequence pressure cyp 3a disease cortisol levels 22/23ek polymorphism skin cancer mutation value men study decrease hsd 11b 11- hsd 1 reference dementia glucocorticoid resistance




7 Most Recent Publications

The influence of the location of the lesion on the absolute risk of the development of skin cancer in a patient with actinic keratosis (Article)
Smit, P. Plomp, E. Neumann, H.A.M. Thio, H.B.
2012-10-16
The skin-blanching assay (Article)
Smit, P. Neumann, H.A.M. Thio, H.B.
2012-10-01
Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia. (Article)
Smit, P. Dekker, M.J.H.J. Jong, F.J. de Beld, A.W. van den Koper, J.W. Pols, H.A.P. Brinkmann, A.O. Jong, F.H. de Breteler, M.M.B. Lamberts, S.W.J.
2007-01-01
Factors Determining Glucocorticoid Sensitivity in Man (Doctoral Thesis)
Smit, P.
2006-11-01
Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression. (Article)
Russcher, H. Smit, P. Akker, E.L.T. van den Rossum, E.F.C. van Brinkmann, A.O. Jong, F.H. de Lamberts, S.W.J. Koper, J.W.
2005-10-01
A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels. (Article)
Smit, P. Schaik, R.H.N. van Werf, M.J. van der Beld, A.W. van den Koper, J.W. Lindemans, J. Pols, H.A.P. Brinkmann, A.O. Jong, F.H. de Lamberts, S.W.J.
2005-09-01
Differential regulation of synthetic glucocorticoids on gene expression levels of glucocorticoid-induced leucine zipper and interleukin-2. (Article)
Smit, P. Russcher, H. Jong, F.H. de Brinkmann, A.O. Lamberts, S.W.J. Koper, J.W.
2005-05-01