http://hdl.handle.net/1765/10006

Measurements of interrupter resistance: reference values for children 3-13 yrs of age


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The interrupter technique is a convenient and sensitive technique for studying airway function in subjects who cannot actively participate in (forced) ventilatory function tests. Reference values for preschool children exist but are lacking for children >7 yrs. Reference values were obtained for expiratory interrupter resistance (R(int,e)) in 208 healthy Dutch Caucasian children 3-13 yrs of age. A curvilinear relationship between R(int,e) and height was observed, similar to published airways resistance data measured by plethysmography. No significant differences in cross-sectional trend or level of R(int,e) were observed according to sex. It was found that Z-scores could be used to express individual R(int,e) values and to describe intra- and interindividual differences based on the reference equation: 10logR(int,e)=0.645-0.00668x standing height (cm) kPa x L(-1) x s(-1) and residual SD (0.093 kPa x L(-1) x s(-1)). Expiratory interrupter resistance provides a tool for clinical and epidemiological assessment of airway function in a large age range.



Keywords


Automatically Extracted Terms
  • children
  • measurement
  • resistance
  • reference
  • height
  • airway
  • reference values
  • interrupter technique
  • interrupter
  • value
  • technique
  • study
  • model
  • respir
  • function
  • airway resistance
  • equation
  • reference equations
  • reference equation
  • pressure


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