Candida krusei transmission among hematology patients resolved by adapted antifungal prophylaxis and infection control measures.
March 2006
Article
volume 44, issue 3 pp 1111-1114.
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A sudden increase in neutropenic hematology patients with Candida krusei colonization and bacteremia prompted a longitudinal epidemiological investigation. We identified 39 patients; 13 developed candidemia, and three died; 25 patients carried the same genotype. We intervened by changing antifungal prophylaxis and implementing strict infection control measures. The incidence dropped immediately.
Keywords
- Humans
- Netherlands/epidemiology
- Longitudinal Studies
- Genotype
- Neutropenia/complications
- Antifungal Agents/administration & dosage
- Candida/genetics/isolation & purification
- Candidiasis/epidemiology/microbiology/prevention & control/*transmission
- Fungemia/epidemiology/microbiology/prevention & control
- Hematologic Diseases/complications
