Liposomal targeting of antimicrobial agents to bacterial infections
(Het doelgericht afleveren van anti-microbiele middelen aan bacteriele infecties middels liposomen)
2001-02-07
Doctoral Thesis
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Failure of antimicrobial treatment is observed frequently in hospitalized patients resulting in morbidity and mortality, A possible way to improve antimicrobial treatment is the targeted delivery of antimicrobial agents, This thesis describes a study on tihe use of long-Circulating liposomes for the targeted delivery of antimicrobial agents to sites of bacterial infections, In this chapter an introduction is given on the use of targeted drug delivery in infectious diseases, which is followed by the aims and outline of this thesis.
Supervisors
(promotores):
The
author
wishes to thank:
NWO,
Dr. Ir. van de Laar Stichting,
Dr. Saal van Zwanenbergstichting
Keywords
Automatically Extracted Terms
- liposomes
- localization
- liposome
- infection
- circulation
- treatment
- blood
- result
- gentamicin
- tissue
- concentration
- survival
- study
- effect
- model
- target
- pneumoniae
- aminoglycoside
- le-gen
- agent
