Human papillomavirus and natural history of cervical intraepithelial neoplasia : clinical consequences

(Humaan Papillomavirus en het natuurlijk beloop van Cervicale lntraepitheliale Neoplasie: klinische consequenties)


Doctoral Thesis
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Cervical cancer is the second most common cancer in women world-wide after breast cancer. Each year, there are approximately 437,000 new cases of invasive cancer of the cervix diagnosed and more than 200,000 women die from the disease, 79% of which occur in developing countries. In the Netherlands approximately 715 new cases of cervical cancer are diagnosed each year with an age-standardised incidence rate of 8,6 new cases per 1 00,000 women. The age-standardised mortality rate for the Netherlands has been estimated at 2,4 deaths per 1 00,000 women with a total of 234 deaths reported in 1995. The average age-standardised mortality rate of developing countries is 2,5 f1mes that of industrialised areas.


The author wishes to thank:

Dutch Prevention Fund/Zorg Onderzoek Nederland,
Digene,
Cytyc Europe,
3M Pharma Nederland,
Schering Nederland BV,
Ferring BV,
Organon Nederland BV,
Rovers Medical Devices BV,
Werkgroep Cervix Uteri


Keywords


Automatically Extracted Terms
  • women
  • cancer
  • smear
  • month
  • study
  • cytology
  • infection
  • lesion
  • screening
  • hpv testing
  • testing
  • dyskaryosi
  • papillomaviru
  • follow-up
  • result
  • clearance
  • treatment
  • regression
  • hpv clearance
  • baseline